XAVIER DANGLEMONT DE TASSIGNY

Categoría
Profesor Contratado Doctor

Contacto

Correo electrónico
Área
Fisiología

Investigación

Grupo de investigación

FISIOLOGIA CELULAR Y BIOFISICA (F.C.B.)

Proyectos y contratos de investigación

Neuroprotection in Parkinson's disease; a potential therapy based on stimulation of endogenous GDNF production (XDTBBVA2015 - Investigador Principal Joven)
Red de Terapia Celular (TerCel) (RD16/0011/0025 - Investigador/a)
Molecular mechanism of acute oxygen sensing (PRJ201502629 - Participante)
"Molecular mechanisms of acute oxygen sensing (OXYGENSENSING)" (2629/0805 - Investigador/a)
Sensibilidad al Oxígeno y Neurodegeneración (SAF2012-39343 - Investigador/a)
Efectos de la hipoxia crónica sobre la neurogénesis en el adulto: protección y rescate del nicho neurogénico (CP12/03217 - Investigador Principal Joven)

Asistencia a congresos

D'anglemont De Tassigny, Xavier:
Pharmacological stimulation of endogenous GDNF in the striatum: towards a future neuroprotective therapy in Parkinson¿s disease?. Sesión no plenaria en Congreso. VI International Congress on Research and Innovation in Neurodegenerative Diseases. XII CIBERNED Scientific Forum.. - Santiago de Compostela (A Coruña), España. 2018
D'anglemont De Tassigny, Xavier:
Towards a specific stimulation of endogenous GDNF production by striatal parvalbumin interneurons. Comunicación en congreso. International Conference on Neurotrophic Factors 2018. - Salamanca, España. 2018
D'anglemont De Tassigny, Xavier;Enterría-Morales, Daniel;Lopez-Lopez, Ivette;Lopez-Barneo, Jose:
Transcriptomic changes in parvalbumin positive interneurons expressing Cre recombinase. Poster en Congreso. SfN Annual Meeting. WASHINGTON DC (EEUU). 2017
Enterría-Morales, Daniel;Lopez-Lopez, Ivette;Lopez-Barneo, Jose;D'anglemont De Tassigny, Xavier:
Molecular insights into the endogenous GDNF expression of striatal parvalbumin neurons: a possible tool for neuroprotective therapy for Parkinson¿s di. Poster en Congreso. SfN Annual Meeting. WASHINGTON DC (EEUU). 2017
D'anglemont De Tassigny, Xavier;Enterría-Morales, Daniel;Lopez-Lopez, Ivette;Lopez-Barneo, Jose:
Stimulation of endogenous striatal GDNF: a neuroprotective therapy for Parkinson¿s disease?. Poster en Congreso. NeuroFrance. BURDEOS (FRANCIA). 2017

Artículos publicados

Enterría-Morales, Daniel;Lopez-Lopez, Ivette;Lopez-Barneo, Jose;D'anglemont De Tassigny, Xavier:
Molecular targets for endogenous glial cell line-derived neurotrophic factor modulation in striatal parvalbumin interneurons. Brain Communications. 2020. Vol: 2. Núm: 2. 10.1093/braincomms/fcaa105.
Enterría-Morales, Daniel;Lopez-Lopez, Ivette;Lopez-Barneo, Jose;D'anglemont De Tassigny, Xavier:
Role of glial cell line-derived neurotrophic factor in the maintenance of adult mesencephalic catecholaminergic neurons. Movement disorders. 2020. 10.1002/mds.27986.
Dong, C;Helton, Es;Zhou, P;Ouyang, X;D'anglemont De Tassigny, Xavier;Pascual, Alberto;Lopez-Barneo, Jose;Ubogu, Ee:
Glial-derived neurotrophic factor is essential for blood-nerve barrier functional recovery in an experimental murine model of traumatic peripheral neu. Tissue Barriers. 2018. Vol: 6. Núm: 2. Pág. 1-22. 10.1080/21688370.2018.1479570.
D'anglemont De Tassigny, Xavier;Jayasena, Channa;Murphy, Kevin G;Dhillo, Waljit S;Colledge, William H:
Mechanistic insights into the more potent effect of KP-54 compared to KP-10 in vivo. PLoS One. 2017. Núm: e0176821. 10.1371/journal.pone.0176821.
D'anglemont De Tassigny, Xavier:
Outlook on the neuroprotective effect of estrogen.. Neural Regeneration Research. 2017. Vol: 12. Núm: 11. Pág. 1799-1800. 10.4103/1673-5374.219036.
Enterría-Morales, Daniel;Lopez-Lopez, Ivette;Lopez-Barneo, Jose;D'anglemont De Tassigny, Xavier:
Striatal GDNF Production Is Independent to Circulating Estradiol Level Despite Pan-Neuronal Activation in the Female Mouse.. PLoS One. 2016. Vol: 11. Núm: 10. 10.1371/journal.pone.0164391.
D'anglemont De Tassigny, Xavier;Pascual, Alberto;Lopez-Barneo, Jose:
GDNF-based therapies, GDNF-producing interneurons, and trophic support of the dopaminergic nigrostriatal pathway. Implications for Parkinson's disease. Frontiers in Neuroanatomy. 2015. Vol: 9. Núm: 10. 10.3389/fnana.2015.00010. eCollection 2015.
D'anglemont De Tassigny, Xavier;Pardal-Redondo, Ricardo;Lopez-Lopez, Ivette;Lopez-Barneo, Jose:
Resistance of subventricular neural stem cells to chronic hypoxemia despite structural disorganization of the germinal center and impairment of neuron. Hypoxia. 2015. Núm: 3. Pág. 15-33. 10.2147/HP.S78248.
Bellefontaine, Charlotte;Chachlaki, Konstantina;Parkhash, Jyoti;Vanacker, Charlotte;Colledge, William H.;D'anglemont De Tassigny, Xavier;Garthwaite, John;Bouret, Sebastien G.;Prevot, Vincent:
Leptin-dependent neuronal NO signaling in the preoptic hypothalamus facilitates reproduction.. Journal of Clinical Investigation. 2014. Vol: 128. Núm: 6. Pág. 2550-2559. 10.1172/JCI65928.
D'anglemont De Tassigny, Xavier:
Kisspeptin-GPR54 signaling in mouse NO-synthesizing neurons participates in the hypothalamic control of ovulation.. The Journal of Neuroscience. 2012. Vol: 32. Núm: 3. Pág. 932-945. 10.1523/JNEUROSCI.4765-11.2012.
D'anglemont De Tassigny, Xavier:
Frequency-dependent recruitment of fast amino acid and slow neuropeptide neurotransmitter release controls gonadotropin-releasing hormone neuron excit. The Journal of Neuroscience. 2011. Vol: 31. Núm: 7. Pág. 2421-2430. 10.1523/JNEUROSCI.5759-10.2011.
D'anglemont De Tassigny, Xavier:
Kisspeptin neurons co-express met-enkephalin and galanin in the rostral periventricular region of the female mouse hypothalamus.. The Journal of Comparative Neurology. 2011. Vol: 519. Núm: 17. Pág. 3456-3469. 10.1002/cne.22716.
D'anglemont De Tassigny, Xavier:
The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent. BMC Genomics. 2011. 10.1186/1471-2164-12-209.
D'anglemont De Tassigny, Xavier:
Inotropic action of the puberty hormone kisspeptin in rat, mouse and human: cardiovascular distribution and characteristics of the kisspeptin receptor. PLoS One. 2011. Vol: 6. Núm: 11. 10.1371/journal.pone.0027601.
D'anglemont De Tassigny, Xavier:
Nitric oxide as key mediator of neuron-to-neuron and endothelia-to-glia communication involved in the neuroendocrine control of reproduction.. Neuroendocrinology. 2011. Vol: 93. Núm: 2. Pág. 74-89. 10.1159/000324147.
D'anglemont De Tassigny, Xavier:
Mll5 is required for normal spermatogenesis.. PLoS One. 2011. Vol: 6. Núm: 11. 10.1371/journal.pone.0027127.
D'anglemont De Tassigny, Xavier:
The role of kisspeptin signaling in reproduction.. Physiology. 2010. Vol: 25. Núm: 4. Pág. 207-217. 10.1152/physiol.00009.2010.
D'anglemont De Tassigny, Xavier:
Role of estradiol in the dynamic control of tanycyte plasticity mediated by vascular endothelial cells in the median eminence.. Endocrinology. 2010. Vol: 151. Núm: 4. Pág. 1760-1772. 10.1210/en.2009-0870.
D'anglemont De Tassigny, Xavier:
Mouse models to study the central regulation of puberty.. Molecular and Cellular Endocrinology. 2010. Vol: 324. Núm: 1-2. Pág. 12-20. 10.1016/j.mce.2010.01.015.
D'anglemont De Tassigny, Xavier:
Distribution and postnatal development of Gpr54 gene expression in mouse brain and gonadotropin-releasing hormone neurons.. Endocrinology. 2010. Vol: 151. Núm: 1. Pág. 312-321. doi: 10.1210/en.2009-0552.
D'anglemont De Tassigny, Xavier:
Function-related structural plasticity of the GnRH system: a role for neuronal-glial-endothelial interactions.. Frontiers in Neuroendocrinology. 2010. Vol: 31. Núm: 3. Pág. 241-258. 10.1016/j.yfrne.2010.05.003.
D'anglemont De Tassigny, Xavier:
Kisspeptin signaling is required for peripheral but not central stimulation of gonadotropin-releasing hormone neurons by NMDA.. The Journal of Neuroscience. 2010. Vol: 30. Núm: 25. Pág. 8581-8590. 10.1523/JNEUROSCI.5486-09.2010.
D'anglemont De Tassigny, Xavier:
Phosphorylation of N-methyl-D-aspartic acid receptor-associated neuronal nitric oxide synthase depends on estrogens and modulates hypothalamic nitric . Endocrinology. 2010. Vol: 151. Núm: 6. Pág. 2723-2735. 10.1210/en.2010-0007.
D'anglemont De Tassigny, Xavier:
Distribution of kisspeptin neurones in the adult female mouse brain.. Journal of Neuroendocrinology. 2009. Vol: 21. Núm: 8. Pág. 673-682. 10.1111/j.1365-2826.2009.01892.x.
D'anglemont De Tassigny, Xavier:
Estradiol induces physical association of neuronal nitric oxide synthase with NMDA receptor and promotes nitric oxide formation via estrogen receptor . Journal of Neurochemistry. 2009. Vol: 109. Núm: 1. Pág. 214-224. 10.1111/j.1471-4159.2009.05949.x.
D'anglemont De Tassigny, Xavier:
The role of kisspeptin signalling in the regulation of the GnRH-gonadotrophin ovarian axis in mice.. Annales d'Endocrinologie. 2008. Vol: 71. Núm: 3. Pág. 198-200. 10.1016/j.ando.2010.02.011.
D'anglemont De Tassigny, Xavier:
Kisspeptin-GPR54 signaling is essential for preovulatory gonadotropin-releasing hormone neuron activation and the luteinizing hormone surge.. The Journal of Neuroscience. 2008. Vol: 28. Núm: 35. Pág. 8691-8697. 10.1523/JNEUROSCI.1775-08.2008.
D'anglemont De Tassigny, Xavier:
Coupling of neuronal nitric oxide synthase to NMDA receptors via postsynaptic density-95 depends on estrogen and contributes to the central control of. The Journal of Neuroscience. 2007. Vol: 27. Núm: 23. Pág. 6103-6114.
D'anglemont De Tassigny, Xavier:
Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene.. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2007. Vol: 104. Núm: 25. Pág. 10714-10719.

Patentes

Lopez-Barneo, Jose;D'anglemont De Tassigny, Xavier;Enterría-Morales, Daniel;Lopez-Lopez, Ivette: Composiciones capaces de modular la estimulación de GDNF endógeno para el tratamiento de enfermedades neurodegenerativas. Número de patente:

Tesis dirigidas o codirigidas

(Doctorando no grabado):
Estimulación del GDNF endógeno en el estriado de ratón.. Tesis Doctoral. 2019