Directorio
XAVIER DANGLEMONT DE TASSIGNY
Categoría
Profesor Contratado Doctor
Contacto
Correo electrónico
Departamento
Área
Fisiología
Docencia
Investigación
Proyectos y contratos de investigación
Neuroprotection in Parkinson's disease; a potential therapy based on stimulation of endogenous GDNF production (XDTBBVA2015 - Investigador Principal Joven)
Red de Terapia Celular (TerCel) (RD16/0011/0025 - Investigador/a)
Molecular mechanism of acute oxygen sensing (PRJ201502629 - Participante)
"Molecular mechanisms of acute oxygen sensing (OXYGENSENSING)" (2629/0805 - Investigador/a)
Sensibilidad al Oxígeno y Neurodegeneración (SAF2012-39343 - Investigador/a)
Efectos de la hipoxia crónica sobre la neurogénesis en el adulto: protección y rescate del nicho neurogénico (CP12/03217 - Investigador Principal Joven)
Asistencia a congresos
D'anglemont De Tassigny, Xavier:
Pharmacological stimulation of endogenous GDNF in the striatum: towards a future neuroprotective therapy in Parkinson¿s disease?. Sesión no plenaria en Congreso. VI International Congress on Research and Innovation in Neurodegenerative Diseases. XII CIBERNED Scientific Forum.. - Santiago de Compostela (A Coruña), España. 2018
Pharmacological stimulation of endogenous GDNF in the striatum: towards a future neuroprotective therapy in Parkinson¿s disease?. Sesión no plenaria en Congreso. VI International Congress on Research and Innovation in Neurodegenerative Diseases. XII CIBERNED Scientific Forum.. - Santiago de Compostela (A Coruña), España. 2018
D'anglemont De Tassigny, Xavier:
Towards a specific stimulation of endogenous GDNF production by striatal parvalbumin interneurons. Comunicación en congreso. International Conference on Neurotrophic Factors 2018. - Salamanca, España. 2018
Towards a specific stimulation of endogenous GDNF production by striatal parvalbumin interneurons. Comunicación en congreso. International Conference on Neurotrophic Factors 2018. - Salamanca, España. 2018
D'anglemont De Tassigny, Xavier;Enterría-Morales, Daniel;Lopez-Lopez, Ivette;Lopez-Barneo, Jose:
Transcriptomic changes in parvalbumin positive interneurons expressing Cre recombinase. Poster en Congreso. SfN Annual Meeting. WASHINGTON DC (EEUU). 2017
Transcriptomic changes in parvalbumin positive interneurons expressing Cre recombinase. Poster en Congreso. SfN Annual Meeting. WASHINGTON DC (EEUU). 2017
Enterría-Morales, Daniel;Lopez-Lopez, Ivette;Lopez-Barneo, Jose;D'anglemont De Tassigny, Xavier:
Molecular insights into the endogenous GDNF expression of striatal parvalbumin neurons: a possible tool for neuroprotective therapy for Parkinson¿s di. Poster en Congreso. SfN Annual Meeting. WASHINGTON DC (EEUU). 2017
Molecular insights into the endogenous GDNF expression of striatal parvalbumin neurons: a possible tool for neuroprotective therapy for Parkinson¿s di. Poster en Congreso. SfN Annual Meeting. WASHINGTON DC (EEUU). 2017
D'anglemont De Tassigny, Xavier;Enterría-Morales, Daniel;Lopez-Lopez, Ivette;Lopez-Barneo, Jose:
Stimulation of endogenous striatal GDNF: a neuroprotective therapy for Parkinson¿s disease?. Poster en Congreso. NeuroFrance. BURDEOS (FRANCIA). 2017
Stimulation of endogenous striatal GDNF: a neuroprotective therapy for Parkinson¿s disease?. Poster en Congreso. NeuroFrance. BURDEOS (FRANCIA). 2017
Artículos publicados
Enterría-Morales, Daniel;Lopez-Lopez, Ivette;Lopez-Barneo, Jose;D'anglemont De Tassigny, Xavier:
Role of glial cell line-derived neurotrophic factor in the maintenance of adult mesencephalic catecholaminergic neurons. Movement disorders. 2020. 10.1002/mds.27986.
Role of glial cell line-derived neurotrophic factor in the maintenance of adult mesencephalic catecholaminergic neurons. Movement disorders. 2020. 10.1002/mds.27986.
Enterría-Morales, Daniel;Lopez-Lopez, Ivette;Lopez-Barneo, Jose;D'anglemont De Tassigny, Xavier:
Molecular targets for endogenous glial cell line-derived neurotrophic factor modulation in striatal parvalbumin interneurons. Brain Communications. 2020. Vol: 2. Núm: 2. 10.1093/braincomms/fcaa105.
Molecular targets for endogenous glial cell line-derived neurotrophic factor modulation in striatal parvalbumin interneurons. Brain Communications. 2020. Vol: 2. Núm: 2. 10.1093/braincomms/fcaa105.
Dong, C;Helton, Es;Zhou, P;Ouyang, X;D'anglemont De Tassigny, Xavier;Pascual, Alberto;Lopez-Barneo, Jose;Ubogu, Ee:
Glial-derived neurotrophic factor is essential for blood-nerve barrier functional recovery in an experimental murine model of traumatic peripheral neu. Tissue Barriers. 2018. Vol: 6. Núm: 2. Pág. 1-22. 10.1080/21688370.2018.1479570.
Glial-derived neurotrophic factor is essential for blood-nerve barrier functional recovery in an experimental murine model of traumatic peripheral neu. Tissue Barriers. 2018. Vol: 6. Núm: 2. Pág. 1-22. 10.1080/21688370.2018.1479570.
D'anglemont De Tassigny, Xavier;Jayasena, Channa;Murphy, Kevin G;Dhillo, Waljit S;Colledge, William H:
Mechanistic insights into the more potent effect of KP-54 compared to KP-10 in vivo. PLoS One. 2017. Núm: e0176821. 10.1371/journal.pone.0176821.
Mechanistic insights into the more potent effect of KP-54 compared to KP-10 in vivo. PLoS One. 2017. Núm: e0176821. 10.1371/journal.pone.0176821.
D'anglemont De Tassigny, Xavier:
Outlook on the neuroprotective effect of estrogen.. Neural Regeneration Research. 2017. Vol: 12. Núm: 11. Pág. 1799-1800. 10.4103/1673-5374.219036.
Outlook on the neuroprotective effect of estrogen.. Neural Regeneration Research. 2017. Vol: 12. Núm: 11. Pág. 1799-1800. 10.4103/1673-5374.219036.
Enterría-Morales, Daniel;Lopez-Lopez, Ivette;Lopez-Barneo, Jose;D'anglemont De Tassigny, Xavier:
Striatal GDNF Production Is Independent to Circulating Estradiol Level Despite Pan-Neuronal Activation in the Female Mouse.. PLoS One. 2016. Vol: 11. Núm: 10. 10.1371/journal.pone.0164391.
Striatal GDNF Production Is Independent to Circulating Estradiol Level Despite Pan-Neuronal Activation in the Female Mouse.. PLoS One. 2016. Vol: 11. Núm: 10. 10.1371/journal.pone.0164391.
D'anglemont De Tassigny, Xavier;Pardal-Redondo, Ricardo;Lopez-Lopez, Ivette;Lopez-Barneo, Jose:
Resistance of subventricular neural stem cells to chronic hypoxemia despite structural disorganization of the germinal center and impairment of neuron. Hypoxia. 2015. Núm: 3. Pág. 15-33. 10.2147/HP.S78248.
Resistance of subventricular neural stem cells to chronic hypoxemia despite structural disorganization of the germinal center and impairment of neuron. Hypoxia. 2015. Núm: 3. Pág. 15-33. 10.2147/HP.S78248.
D'anglemont De Tassigny, Xavier;Pascual, Alberto;Lopez-Barneo, Jose:
GDNF-based therapies, GDNF-producing interneurons, and trophic support of the dopaminergic nigrostriatal pathway. Implications for Parkinson's disease. Frontiers in Neuroanatomy. 2015. Vol: 9. Núm: 10. 10.3389/fnana.2015.00010. eCollection 2015.
GDNF-based therapies, GDNF-producing interneurons, and trophic support of the dopaminergic nigrostriatal pathway. Implications for Parkinson's disease. Frontiers in Neuroanatomy. 2015. Vol: 9. Núm: 10. 10.3389/fnana.2015.00010. eCollection 2015.
Bellefontaine, Charlotte;Chachlaki, Konstantina;Parkhash, Jyoti;Vanacker, Charlotte;Colledge, William H.;D'anglemont De Tassigny, Xavier;Garthwaite, John;Bouret, Sebastien G.;Prevot, Vincent:
Leptin-dependent neuronal NO signaling in the preoptic hypothalamus facilitates reproduction.. Journal of Clinical Investigation. 2014. Vol: 128. Núm: 6. Pág. 2550-2559. 10.1172/JCI65928.
Leptin-dependent neuronal NO signaling in the preoptic hypothalamus facilitates reproduction.. Journal of Clinical Investigation. 2014. Vol: 128. Núm: 6. Pág. 2550-2559. 10.1172/JCI65928.
D'anglemont De Tassigny, Xavier:
Kisspeptin-GPR54 signaling in mouse NO-synthesizing neurons participates in the hypothalamic control of ovulation.. The Journal of Neuroscience. 2012. Vol: 32. Núm: 3. Pág. 932-945. 10.1523/JNEUROSCI.4765-11.2012.
Kisspeptin-GPR54 signaling in mouse NO-synthesizing neurons participates in the hypothalamic control of ovulation.. The Journal of Neuroscience. 2012. Vol: 32. Núm: 3. Pág. 932-945. 10.1523/JNEUROSCI.4765-11.2012.
D'anglemont De Tassigny, Xavier:
Inotropic action of the puberty hormone kisspeptin in rat, mouse and human: cardiovascular distribution and characteristics of the kisspeptin receptor. PLoS One. 2011. Vol: 6. Núm: 11. 10.1371/journal.pone.0027601.
Inotropic action of the puberty hormone kisspeptin in rat, mouse and human: cardiovascular distribution and characteristics of the kisspeptin receptor. PLoS One. 2011. Vol: 6. Núm: 11. 10.1371/journal.pone.0027601.
D'anglemont De Tassigny, Xavier:
Nitric oxide as key mediator of neuron-to-neuron and endothelia-to-glia communication involved in the neuroendocrine control of reproduction.. Neuroendocrinology. 2011. Vol: 93. Núm: 2. Pág. 74-89. 10.1159/000324147.
Nitric oxide as key mediator of neuron-to-neuron and endothelia-to-glia communication involved in the neuroendocrine control of reproduction.. Neuroendocrinology. 2011. Vol: 93. Núm: 2. Pág. 74-89. 10.1159/000324147.
D'anglemont De Tassigny, Xavier:
The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent. BMC Genomics. 2011. 10.1186/1471-2164-12-209.
The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent. BMC Genomics. 2011. 10.1186/1471-2164-12-209.
D'anglemont De Tassigny, Xavier:
Mll5 is required for normal spermatogenesis.. PLoS One. 2011. Vol: 6. Núm: 11. 10.1371/journal.pone.0027127.
Mll5 is required for normal spermatogenesis.. PLoS One. 2011. Vol: 6. Núm: 11. 10.1371/journal.pone.0027127.
D'anglemont De Tassigny, Xavier:
Frequency-dependent recruitment of fast amino acid and slow neuropeptide neurotransmitter release controls gonadotropin-releasing hormone neuron excit. The Journal of Neuroscience. 2011. Vol: 31. Núm: 7. Pág. 2421-2430. 10.1523/JNEUROSCI.5759-10.2011.
Frequency-dependent recruitment of fast amino acid and slow neuropeptide neurotransmitter release controls gonadotropin-releasing hormone neuron excit. The Journal of Neuroscience. 2011. Vol: 31. Núm: 7. Pág. 2421-2430. 10.1523/JNEUROSCI.5759-10.2011.
D'anglemont De Tassigny, Xavier:
Kisspeptin neurons co-express met-enkephalin and galanin in the rostral periventricular region of the female mouse hypothalamus.. The Journal of Comparative Neurology. 2011. Vol: 519. Núm: 17. Pág. 3456-3469. 10.1002/cne.22716.
Kisspeptin neurons co-express met-enkephalin and galanin in the rostral periventricular region of the female mouse hypothalamus.. The Journal of Comparative Neurology. 2011. Vol: 519. Núm: 17. Pág. 3456-3469. 10.1002/cne.22716.
D'anglemont De Tassigny, Xavier:
Distribution and postnatal development of Gpr54 gene expression in mouse brain and gonadotropin-releasing hormone neurons.. Endocrinology. 2010. Vol: 151. Núm: 1. Pág. 312-321. doi: 10.1210/en.2009-0552.
Distribution and postnatal development of Gpr54 gene expression in mouse brain and gonadotropin-releasing hormone neurons.. Endocrinology. 2010. Vol: 151. Núm: 1. Pág. 312-321. doi: 10.1210/en.2009-0552.
D'anglemont De Tassigny, Xavier:
Kisspeptin signaling is required for peripheral but not central stimulation of gonadotropin-releasing hormone neurons by NMDA.. The Journal of Neuroscience. 2010. Vol: 30. Núm: 25. Pág. 8581-8590. 10.1523/JNEUROSCI.5486-09.2010.
Kisspeptin signaling is required for peripheral but not central stimulation of gonadotropin-releasing hormone neurons by NMDA.. The Journal of Neuroscience. 2010. Vol: 30. Núm: 25. Pág. 8581-8590. 10.1523/JNEUROSCI.5486-09.2010.
D'anglemont De Tassigny, Xavier:
Phosphorylation of N-methyl-D-aspartic acid receptor-associated neuronal nitric oxide synthase depends on estrogens and modulates hypothalamic nitric . Endocrinology. 2010. Vol: 151. Núm: 6. Pág. 2723-2735. 10.1210/en.2010-0007.
Phosphorylation of N-methyl-D-aspartic acid receptor-associated neuronal nitric oxide synthase depends on estrogens and modulates hypothalamic nitric . Endocrinology. 2010. Vol: 151. Núm: 6. Pág. 2723-2735. 10.1210/en.2010-0007.
D'anglemont De Tassigny, Xavier:
The role of kisspeptin signaling in reproduction.. Physiology. 2010. Vol: 25. Núm: 4. Pág. 207-217. 10.1152/physiol.00009.2010.
The role of kisspeptin signaling in reproduction.. Physiology. 2010. Vol: 25. Núm: 4. Pág. 207-217. 10.1152/physiol.00009.2010.
D'anglemont De Tassigny, Xavier:
Role of estradiol in the dynamic control of tanycyte plasticity mediated by vascular endothelial cells in the median eminence.. Endocrinology. 2010. Vol: 151. Núm: 4. Pág. 1760-1772. 10.1210/en.2009-0870.
Role of estradiol in the dynamic control of tanycyte plasticity mediated by vascular endothelial cells in the median eminence.. Endocrinology. 2010. Vol: 151. Núm: 4. Pág. 1760-1772. 10.1210/en.2009-0870.
D'anglemont De Tassigny, Xavier:
Function-related structural plasticity of the GnRH system: a role for neuronal-glial-endothelial interactions.. Frontiers in Neuroendocrinology. 2010. Vol: 31. Núm: 3. Pág. 241-258. 10.1016/j.yfrne.2010.05.003.
Function-related structural plasticity of the GnRH system: a role for neuronal-glial-endothelial interactions.. Frontiers in Neuroendocrinology. 2010. Vol: 31. Núm: 3. Pág. 241-258. 10.1016/j.yfrne.2010.05.003.
D'anglemont De Tassigny, Xavier:
Mouse models to study the central regulation of puberty.. Molecular and Cellular Endocrinology. 2010. Vol: 324. Núm: 1-2. Pág. 12-20. 10.1016/j.mce.2010.01.015.
Mouse models to study the central regulation of puberty.. Molecular and Cellular Endocrinology. 2010. Vol: 324. Núm: 1-2. Pág. 12-20. 10.1016/j.mce.2010.01.015.
D'anglemont De Tassigny, Xavier:
Estradiol induces physical association of neuronal nitric oxide synthase with NMDA receptor and promotes nitric oxide formation via estrogen receptor . Journal of Neurochemistry. 2009. Vol: 109. Núm: 1. Pág. 214-224. 10.1111/j.1471-4159.2009.05949.x.
Estradiol induces physical association of neuronal nitric oxide synthase with NMDA receptor and promotes nitric oxide formation via estrogen receptor . Journal of Neurochemistry. 2009. Vol: 109. Núm: 1. Pág. 214-224. 10.1111/j.1471-4159.2009.05949.x.
D'anglemont De Tassigny, Xavier:
Distribution of kisspeptin neurones in the adult female mouse brain.. Journal of Neuroendocrinology. 2009. Vol: 21. Núm: 8. Pág. 673-682. 10.1111/j.1365-2826.2009.01892.x.
Distribution of kisspeptin neurones in the adult female mouse brain.. Journal of Neuroendocrinology. 2009. Vol: 21. Núm: 8. Pág. 673-682. 10.1111/j.1365-2826.2009.01892.x.
D'anglemont De Tassigny, Xavier:
The role of kisspeptin signalling in the regulation of the GnRH-gonadotrophin ovarian axis in mice.. Annales d'Endocrinologie. 2008. Vol: 71. Núm: 3. Pág. 198-200. 10.1016/j.ando.2010.02.011.
The role of kisspeptin signalling in the regulation of the GnRH-gonadotrophin ovarian axis in mice.. Annales d'Endocrinologie. 2008. Vol: 71. Núm: 3. Pág. 198-200. 10.1016/j.ando.2010.02.011.
D'anglemont De Tassigny, Xavier:
Kisspeptin-GPR54 signaling is essential for preovulatory gonadotropin-releasing hormone neuron activation and the luteinizing hormone surge.. The Journal of Neuroscience. 2008. Vol: 28. Núm: 35. Pág. 8691-8697. 10.1523/JNEUROSCI.1775-08.2008.
Kisspeptin-GPR54 signaling is essential for preovulatory gonadotropin-releasing hormone neuron activation and the luteinizing hormone surge.. The Journal of Neuroscience. 2008. Vol: 28. Núm: 35. Pág. 8691-8697. 10.1523/JNEUROSCI.1775-08.2008.
D'anglemont De Tassigny, Xavier:
Coupling of neuronal nitric oxide synthase to NMDA receptors via postsynaptic density-95 depends on estrogen and contributes to the central control of. The Journal of Neuroscience. 2007. Vol: 27. Núm: 23. Pág. 6103-6114.
Coupling of neuronal nitric oxide synthase to NMDA receptors via postsynaptic density-95 depends on estrogen and contributes to the central control of. The Journal of Neuroscience. 2007. Vol: 27. Núm: 23. Pág. 6103-6114.
D'anglemont De Tassigny, Xavier:
Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene.. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2007. Vol: 104. Núm: 25. Pág. 10714-10719.
Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene.. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2007. Vol: 104. Núm: 25. Pág. 10714-10719.
Patentes
Lopez-Barneo, Jose;D'anglemont De Tassigny, Xavier;Enterría-Morales, Daniel;Lopez-Lopez, Ivette: Composiciones capaces de modular la estimulación de GDNF endógeno para el tratamiento de enfermedades neurodegenerativas. Número de patente:
Tesis dirigidas o codirigidas
(Doctorando no grabado):
Estimulación del GDNF endógeno en el estriado de ratón.. Tesis Doctoral. 2019
Estimulación del GDNF endógeno en el estriado de ratón.. Tesis Doctoral. 2019
