MOHAMMED RAFII EL IDRISSI BENHNIA

Categoría
Profesor Contratado Doctor

Contacto

Correo electrónico
Área
Bioquímica y Biología Molecular

Investigación

Grupo de investigación

INMUNOVIROLOGIA (INMUNOVIROLOGIA)

Proyectos y contratos de investigación

Role of a combined antiretroviral treatment including maravirco in the response to hepatitis B and A virus vaccine (Coordinador)
Role of a combined antiretroviral treatment including maraviroc in the response to hepatitis B and A virus vaccine. (2808/0831 - Investigador/a)
Predicción de la respuesta de anticuerpos altamente neutralizante y control del VIH en la colaboración de células TCD4+ (TFH) y ausencia de disfuncion (PI13/01836 - Responsable)
Innate and adaptive Immunity in the Evolution of Lyme Arthritis ()
CD14 and the Immunopathogenesis of Chronic Lyme Disease. (1R01AI05456-01A1 - )
Recognition of bacterial antigens by Natural killer T cells. (RO1 450503 - )
Humoral Immunity to Vaccinia Virus (R01 AI63107 - )
Therapeutic Fully Human Monoclonal Antibodies against Vaccinia Virus and Smallpox (U01 application in response to RFA-AI-07-003 - )
Role of Fc receptors in generating immune protection in vivo against Vaccinia virus (RYC-2010-07419 - 21-04-463B-750 - )
B Cell Eptitope Discovery and Mechanisms of Antibody Protection (25061-65-384 - )
Discovering targets of antibody responses in vaccinia virus and their mechanism of protection ¿B cell Epitope Discovery and Mechanisms of Antibody Pro (BAA NIAID-DAIT-NIH AI2008031 - )

Capítulos en Libros

Rafii-el-idrissi-Benhnia, Mohammed:
Mechanisms of action of melatonin on the human immune system. Membranes versus Nuclear receptors.. Karger Medical and Scientific Publishers. Karger Medical and Scientific Publishers. 1997.
Rafii-el-idrissi-Benhnia, Mohammed:
Mechanisms of action of melatonin on the human immune system. . Pág. 43-51. En: 23. Karger Medical and Scientific Publishers. Karger Medical and Scientific Publishers. 1997.
Rafii-el-idrissi-Benhnia, Mohammed:
Mechanisms of action of melatonin on the human immune system. Membranes versus Nuclear receptors.. Pág. 43-52. KARGER. KARGER. 1996.

Asistencia a congresos

Rosado, Isaac;Leal-Noval, Manuel;Pacheco-Lopez, Yolanda María;Pozo-Balado, Maria Del Mar;De Pablo-Bernal, Rebeca ;Álvarez-Ríos, Ana Isabel;Dominguez, B;Polaino, Mj;Tarancon, Laura;Rafii-el-idrissi-Benhnia, Mohammed;Ruiz-Mateos-Carmona, Ezequiel:
Alteraciones inmunovirológicas de pacientes No Repobladores antes del tratamiento antirretroviral. Poster en Congreso. VI Congreso Nacional GESIDA. Grupo de Estudio de Sida-SEIMC y 8ª Reunión Docente de la Red de Investigación en Sida.. . 2014
De Pablo-Bernal, Rebeca ;Rafii-el-idrissi-Benhnia, Mohammed;Ruiz-Mateos-Carmona, Ezequiel;Leal-Noval, Manuel;Cañizarez, J;Galve, Mi;Ramos, R;Rosado, Isaac;Álvarez-Ríos, Ana Isabel;Carrillo, A;Ferrando-Martínez, Sara;Sanchez, Berta:
Los monocitos de pacientes infectados por VIH bajo TARGA supresor presentan mayor activación ex vivo y mayor respuesta a Lps in vitro que sujetos no i. Poster en Congreso. VI Congreso Nacional GESIDA. Grupo de Estudio de Sida-SEIMC y 8ª Reunión Docente de la Red de Investigación en Sida.. . 2014

Artículos publicados

De Pablo-bernal, Rebeca;Rafii-el-idrissi-Benhnia, Mohammed;Pacheco-Lopez, Yolanda María;Ramos, Raquel;Leal-Noval, Manuel;Ruiz-Mateos-Carmona, Ezequiel;Cañizares, Julio;Rosado, Isaac;Galvá, María Isabel;Álvarez-Ríos, Ana Isabel;Carrillo-Vico, Antonio;Ferrando-Martínez, Sara;Muñoz-fernández, María Angeles;Rafii-el-idrissi Benhnia, Mohammed:
Monocyte Phenotype and Polyfunctionality Are Associated With Elevated Soluble Inflammatory Markers, Cytomegalovirus Infection, and Functional and Cogn. The Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 2016. Vol: Oct;66. Núm: 5. Pág. 643-652. 10.1093/gerona/glv121.
Rafii-el-idrissi-Benhnia, Mohammed:
Immunovirological Efficacy of Once-Daily Maraviroc Plus Ritonavir-Boosted Atazanavir After 48 Weeks in Naive HIV-Infected Patients. Viral Immunology. 2016. Vol: 29. Núm: 8. Pág. 471-477. 10.1089/vim.2016.0046.
Rafii-el-idrissi-Benhnia, Mohammed:
Phenotype and Polyfunctional Deregulation Involving Interleukin 6 (IL-6)¿ and IL-10¿Producing Monocytes in HIV-Infected Patients Receiving Combination. The Journal of Infectious Diseases. 2016. Vol: 213. Núm: 6. Pág. 999-1007. https://doi.org/10.1093/infdis/jiv520.
Méndez-Lagares, Gema;Rafii-el-idrissi-Benhnia, Mohammed:
Maraviroc contributes to the restoration of the homeostasis of regulatory T-cell subsets in antiretroviral-naive HIV-infected subjects. Clinical Microbiology and Infection. 2016. Vol: 22. Núm: 5. Pág. 461. e1-461. e5-461. e1-461. e5. https://doi.org/10.1016/j.cmi.2015.12.025.
Rafii-el-idrissi-Benhnia, Mohammed:
IFNL4 ss469415590 polymorphism is associated with unfavourable clinical and immunological status in HIV-infected individuals. Clinical Microbiology and Infection. 2015. Vol: 21. Núm: 3. Pág. 289.e1-4-289.e1-4. 10.1016/j.cmi.2014.10.012.
Rafii-el-idrissi-Benhnia, Mohammed:
Structural and functional characterization of anti-A33 antibodies reveal a potent cross-species orthopoxviruses neutralizer. PLoS Pathogens. 2015. Vol: 11. Núm: 9. 10.1371/journal.ppat.1005148.
Rafii-el-idrissi-Benhnia, Mohammed:
Maraviroc Clinical Test (MCT) as an alternative tool to decide CCR5-antagonists prescription in naïve HIV-infected patients. Antiviral Research. 2015. Vol: 121. Pág. 94-96. https://doi.org/10.1016/j.antiviral.2015.06.018.
Romero-Sánchez, Maria Concepción;Abad-Carrillo, Maria Antonia;Leal-Noval, Manuel;Ruiz-Mateos-Carmona, Ezequiel;Álvarez-Ríos, Ana Isabel;Bernal-morell, E;Genebat, Manuel;Vera, F;Rafii-el-idrissi-Benhnia, Mohammed;Bravo-urbieta, J;Galera-peñaranda, C;De Pablo-Bernal, Rebeca :
Maintenance of virologic efficacy and decrease in levels of beta2-microglobulin, soluble CD40L and soluble CD14 after switching previously treated HIV. Antiviral Research. 2014. Vol: 111. Pág. 26-32. 10.1016/j.antiviral.2014.08.011.
Rafii-el-idrissi-Benhnia, Mohammed:
Using a Combined Computational-Experimental Approach to Predict Antibody-Specific B Cell Epitopes. Structure. 2014. Vol: 22. Núm: 4. Pág. 646-657. 10.1016/j.str.2014.02.003.
Rafii-el-idrissi-Benhnia, Mohammed:
The Challenge of Poxvirus Resistance to Antibody Neutralization. Journal of Virology. 2013. Vol: Feb (87). Núm: 3. Pág. 1289-1289. 10.1128/JVI.02152-12 .
Rafii-el-idrissi-Benhnia, Mohammed:
Unusual features of vaccinia virus extracellular virion form neutralization resistance revealed in human antibody responses to the smallpox vaccine. Journal of Virology. 2013. Vol: 87. Núm: 3. Pág. 1569-1585. 10.1128/JVI.02152-12 .
Rafii-el-idrissi-Benhnia, Mohammed:
Structural and biochemical characterization of the vaccinia virus envelope protein D8 and its recognition by the antibody LA5. Journal of Virology. 2012. Vol: 86. Núm: 15. Pág. 8050-8058. 10.1128/JVI.00836-12.
Rafii-el-idrissi-Benhnia, Mohammed:
B cell-specific expression of B7-2 is required for follicular Th cell function in response to vaccinia virus. The Journal of Immunology. 2011. Vol: 186. Núm: 9. Pág. 5294-5303. 10.4049/jimmunol.1100406.
Rafii-el-idrissi-Benhnia, Mohammed:
Combination therapy of vaccinia virus infection with human anti-H3 and anti-B5 monoclonal antibodies in a small animal model. Antiviral Therapy. 2010. Vol: 15. Núm: 4. Pág. 661-675. 10.3851/IMP1573.
Rafii-el-idrissi-Benhnia, Mohammed:
Heavily Isotype Dependent Protective Activities of Human Antibodies Against the Vaccinia Virus Extracellular Virion Antigen B5. . Journal of Virology. 2009. Vol: 83. Núm: 23. Pág. 12355-12367. 10.1128/JVI.01593-09.
Rafii-el-idrissi-Benhnia, Mohammed:
Vaccinia virus extracellular enveloped virion neutralization in vitro and protection in vivo depend on complement.. Journal of Virology. 2009. Vol: 83. Núm: 3. Pág. 1201-1215. 10.1128/JVI.01797-08.
Rafii-el-idrissi-Benhnia, Mohammed:
Selective CD4 T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities. Immunity. 2008. Vol: 28. Núm: 6. Pág. 847-858. 10.1016/j.immuni.2008.04.018.
Rafii-el-idrissi-Benhnia, Mohammed:
Redundancy and plasticity of neutralizing antibody responses are cornerstone attributes of the human immune response to the smallpox vaccine.. Journal of Virology. 2008. Vol: 82. Núm: 7. Pág. 3751-3768. 10.1128/JVI.02244-07.
Rafii-el-idrissi-Benhnia, Mohammed:
NKT cells prevent chronic joint inflammation after infection with Borrelia burgdorferi. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2008. Vol: 105. Núm: 50. Pág. 19863-19868. 10.1073/pnas.0810519105. .
Rafii-el-idrissi-Benhnia, Mohammed:
Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria. Nature Immunology. 2006. Vol: 7. Núm: 9. Pág. 978-986. 10.1038/ni1380.
Rafii-el-idrissi-Benhnia, Mohammed:
Signaling through CD14 attenuates the inflammatory response to Borrelia burgdorferi, the agent of Lyme disease. The Journal of Immunology. 2005. Vol: 174. Núm: 3. Pág. 1539-1548. 10.4049/jimmunol.174.3.1539.
Rafii-el-idrissi-Benhnia, Mohammed:
Characterization of membrane melatonin receptor in mouse peritoneal macrophages: Inhibition of adenylyl cyclase by a pertussis toxin-sensitive G prote. Journal of Neuroimmunology. 1999. Vol: 95. Núm: 1-2. Pág. 85-94. 10.1016/S0165-5728(98)00268-9.
Rafii-el-idrissi-Benhnia, Mohammed:
Specific binding of Melatonin by purified cell nuclei from spleen and thymus of the rat. Journal of Neuroimmunology. 1998. Vol: June 15 (86). Núm: 2. Pág. 190-197. 10.1016/S0165-5728(98)00048-4.
Rafii-el-idrissi-Benhnia, Mohammed:
Differential adrenergic regulation of rat pineal cyclic AMP and N-acetyltransferase activity during postnatal development: Involvement of G"s and G"1-. Journal of Endocrinology. 1997. Vol: 155. Núm: 5. Pág. 305-312. PMID: 9415065 .
Rafii-el-idrissi-Benhnia, Mohammed:
Melatonin enhaces IL-2 and IFN-gamma production by human circulating CD4+ cells: A possible receptor-mediated mechanism involving Th1 lymphocytes and . The Journal of Immunology. 1997. Vol: 159. Núm: 2. Pág. 574-581. PMID: 9218571.
Rafii-el-idrissi-Benhnia, Mohammed:
Specific binding of 2-[125I]iodomelatonin by rat spleen crude membranes: day-night variations and effect of pinealectomy and continuous light exposure. Journal of Pineal Research. 1996. Vol: Jan;20. Núm: 1. Pág. 33-38. 10.1111/j.1600-079X.1996.tb00236.x.
Rafii-el-idrissi-Benhnia, Mohammed:
Characterization of binding sites for beta-adrenergic agonists and vasoactive intestinal peptide in the rat harderian gland.. Microscopy Research and Technique. 1996. Vol: 34. Núm: 2. Pág. 139-143. 8722708.
Rafii-el-idrissi-Benhnia, Mohammed:
Binding of [125I]iodocyanopindolol by rat harderian gland crude membranes: kinetic characteristics and day-night variations. Bioscience Reports. 1996. Vol: 16. Núm: 5. Pág. 369-377. 8913527.
Rafii-el-idrissi-Benhnia, Mohammed:
Immunomodulatory role of melatonin: specific binding sites in human and rodent lymphoid cells.. Journal of Pineal Research. 1995. Vol: Apr;18. Núm: 3. Pág. 119-126. 10.1111/j.1600-079X.1995.tb00149.x.
Rafii-el-idrissi-Benhnia, Mohammed:
Specific binding of 2-[125I]iodomelatonin by rat splenocytes: characterization and its role on regulation of cyclic AMP production.. Journal of Neuroimmunology. 1995. Vol: Mar;57. Núm: 1-2. Pág. 171-178. 10.1016/0165-5728(94)00182-N.