GONZALO DE GONZALO CALVO

Categoría
Profesor Titular de Universidad

Contacto

Teléfono
Correo electrónico

Departamento

Área
Química Orgánica

Investigación

Grupo de investigación

SINTESIS ESTEREOSELECTIVA (SINTESIS ESTEREOSELECTIVA)

Proyectos y contratos de investigación

Síntesis Estereoselectiva/FQM 263 (PAI 2020) (FQM263-PAI 2020 - Investigador/a)
Solicitud de un cromatógrafo de gases de dos canales, ambos con detector FID para uso en cromatografía quiral (IE17/5850 - Investigador/a)
Adquisición de equipamiento destinado a control y estudios mecanísticos y cinéticos de reacciones orgánicas mediante técnicas espectroscópicas. (EQC2019-005433-P - Investigador/a)
Adquisición de un equipo de Cromatografía de fluidos Supercríticos (HPLC-SFC) (IE19_148 USE - Investigador/a)
Síntesis Estereoselectiva/FQM 263 (PAI 2019) (FQM263-PAI 2019 - Investigador/a)
Síntesis Estereoselectiva/FQM 263 (PAI 2017) (FQM263-PAI 2017 - Investigador/a)
Adquisición de un equipo de cromatografía de Gases con detectores FID y Masas y sistemas de cromatografía FLASH/LC complementados con un sistema de Cr (EQC2018-004416-P - Investigador/a)
Catalizadores, Ligandos, Métodos y Reactivos para Síntesis Organica Selectiva (PID2019-106358GB-C21 - Investigador/a)
Diseño racional de catalizadores quirales avanzados orientado a aplicaciones en catálisis enantioselectiva (P18-FR-644 - Investigador/a)
Red ORFEO-CINQA "Centro de Innovación en Química Avanzada" (RED2018-102387-T - Investigador/a)
Diseño Racional de Catalizadores Quirales Avanzados Orientado a Aplicaciones en Catalisis Enantioselectiva (US-1262867 - Investigador/a)
Adquisición de un equipo de cromatografía líquida de alta resolución y de sistemas para síntesis en continuo, en paralelo y a baja temperatura (UNSE15-CE-2892 - Investigador/a)
Desarrollo y diversificación de sistemas catalíticos innovadores. Aplicaciones en Catálisis asimétrica (CTQ2016-76908-C2-2-P - Investigador/a)
Red de Excelencia en Catálisis Asimétrica (CTQ2016-81893-REDT - Investigador/a)
Red ORFEO-CINQA "Centro de innovación en Química Avanzada" (CTQ2016-81797-REDC - Investigador/a)
Red ORFEO-CINQA "Centro de Innovación en Química Avanzada" (CTQ2014-51912-REDC - Investigador/a)
Red de Excelencia en Catálisis Asimétrica (CTQ2014-55571-REDT - Investigador/a)
Sistemas catalíticos y reactivos de nueva generación para aplicaciones en síntesis asimétrica (CTQ2013-48164-C2-2-P - Investigador/a)
Preparación quimioenzimática de paroxetina y los bloqueantes atenolol y metoprolol (1FD97-0123 - Investigador/a)
Síntesis enzimática de fármacos quirales: Ciclopirrolonas y 1,4-dihidropiridinas (Investigador/a)
Biocatálisis aplicada a la preparación de cuatro productos farmacéuticos (FC-02-PC-CIS01-15 - Investigador/a)
Grupo de Bioorgánica (Proyectos de Excelencia del Principado de Asturias) (Investigador/a)
Post genomic datamining of enzymes for the synthesis of chiral pharmaceutical intermediates DATAGENOM (UE-04-LSHB-CT-2003-503017 - Investigador/a)
Procesos biocatalíticos para la preparación de fármacos enantiopuros (FC-06-PC-019 - Investigador/a)
Química sostenible. Procesos biocatalíticos para la preparación de productos de alto valor añadido: Aplicaciones en organocatálisis y en síntesis de f (MEC-07-CTQ2007-61126 - Investigador/a)
Oxygreen FP7, Effective redesign of oxidative enzymes for green chemistry (Investigador/a)
BIONEXGEN, Developing the next generation of biocatalyst for industrial chemical synthesis (UE-11-BIONEXGEN-266025 - Investigador/a)

Libros publicados

de Gonzalo, Gonzalo;Lavandera, Iván:
Biocatalysis for Practitioners: Techniques, Reactions and Applications. WILEY-VCH. 2021. 978-3-527-34683-7
De Gonzalo-Calvo, Gonzalo;Domínguez De María, Pablo:
Biocatalysis: an Industrial Perspective. ROYAL SOCIETY OF CHEMISTRY. 2017. 978-1-78262-619-0

Capítulos en Libros

de Gonzalo, Gonzalo;Lavandera, Iván:
Enzymatic Commercial Sources. Pág. 467-486. WILEY-VCH. WILEY-VCH. 2021.
De Gonzalo-Calvo, Gonzalo;Lavandera, Iván;Gotor, Vicente:
Recent Advances in Biocatalysis Applied to Organic Synthesis. Pág. 491-527. En: 1. John Wiley & Sons Inc. John Wiley & Sons Inc. 2011.

Asistencia a congresos

De Gonzalo-Calvo, Gonzalo;Görbe, Tamás;Gustafson, Karl;Schreiber, Cynthia;Bäckvall , Jan-e:
Pd(0)CalB-CLEA as bifunctional catalyst for the dynamic kinetic resolution of amines. Comunicación en congreso. 4th Multistep Enzyme Catalyzed Processes Congress. Trondheim, Noruega. 2018
De Gonzalo-Calvo, Gonzalo:
Organocatalyzed synthesis of optically active cyanohydrins starting from alpha-ketoesters. Comunicación en congreso. The 21st International Electronic Conference on Synthetic Organic Chemistry. Sciforum. 2017
De Gonzalo-Calvo, Gonzalo;Fürst, Maximilian;Fraaije, Marco:
Enzymatic sulfoxidations catalyzed by polycyclic ketone monooxygenase. Poster en Congreso. 13th International Symposium on Biocatalysis and Biotransformations. Budapest, Budapest, Hugria. 2017
De Gonzalo-Calvo, Gonzalo;Lassaletta, Jose María;Lassaletta, Jose Maria;Cabrera-Escribano, Francisca:
Chitosan-supported ureas as organocatalysts in asymmetric synthesis. Comunicación en congreso. 13th International Conference of the European Chitin Society - 8th Symposium of the Iberoamerican Chitin Society. Sevilla. 2017
De Gonzalo-Calvo, Gonzalo;Rodríguez, Cristina;Gotor, Vicente:
Immobilization of Baeyer-Villiger monooxygenases in presence of ionic liquids, a simple approach for enzyme recycling. Comunicación en congreso. The 20th International Electronic Conference on Synthetic Organic Chemistry. Sciforum. 2016
De Gonzalo-Calvo, Gonzalo;Rodriguez, Cristina;Gotor, Vicente:
Immobilization of Baeyer-Villiger monooxygenases in presence of ionic liquids, a simple appraoch for enzyme recycling. Comunicación en congreso. 20th Electronic Conference on Synthetic Organic Chemistry. Santiago de Compostela. 2016
Carmona, José Alberto;Serrano-Vallez, Inmaculada;De Gonzalo-Calvo, Gonzalo;Monge-Fernández, David;Fernández-Fernández, Rosario;Lassaletta-Simon, Jose Mª:
Asymetric organocatalytic functionalization of alfa-keto esters. Poster en Congreso. XXVI Reunión Bienal de Química Orgánica de la Real Sociedad Española de Química. Punta Umbría, Huelva. 2016
De Gonzalo-Calvo, Gonzalo;Fernández-Fernández, Rosario;Lassaletta-Simon, Jose Mª:
Organocatalytic Cyanosilylation of alfa-Ketoesters. Comunicación en congreso. XXVI Reunión del Grupo Especializado de Química Orgánica de la Real Sociedad Española de Química. PUNTA UMBRÍA, HUELVA. 2016
De Gonzalo-Calvo, Gonzalo:
Reacciones hetero-carbonil-énicas selectivas sobre alfa-cetoésteres catalizadas por tioureas derivadas de carbohidratos. Comunicación en congreso. XXXV Reunión Bienal de la Real Sociedad Española de Química. A CORUÑA. ESPAÑA. 2015
Serrano-Vallez, Inmaculada;Monge-Fernández, David;De Gonzalo-Calvo, Gonzalo;Fernández-Fernández, Rosario;Lassaletta-Simon, Jose Mª:
REACCIONES HETERO-CARBONIL-ÉNICAS SELECTIVAS SOBRE ALFA-CETOÉSTERES ALIFÁTICOS CATALIZADAS POR TIOUREAS DERIVADAS DE CARBOHIDRATOS. Comunicación en congreso. XXXV Reunión Bienal de la Real Sociedad Española de Química. A CORUÑA. ESPAÑA. 2015
De Gonzalo-Calvo, Gonzalo;Rioz-martínez, Ana;Fraaije, Marco W.:
Procesos oxidativos catalizados por Eugenol oxidasa. Comunicación en congreso. Primeras Jornadas Españolas de Biocatálisis. Madrid, España. 2015
Serrano-Vallez, Inmaculada;Monge-Fernández, David;De Gonzalo-Calvo, Gonzalo;Fernández-Fernández, Rosario;Lassaletta-Simon, Jose Mª:
Enantioselective Heteroenic Reactions of Hydrazones and Aliphatic alfa-Cetoesters Catalyzed by Carbohydratebased Thioureas. Poster en Congreso. 7th Spanish Portuguese Japanese Organic Chemistry Symposium. Sevilla (España). 2015
Lavandera, I.;Bisogno, F. R.;Rioz-martínez, A.;Rodríguez, C.;García-urdiales, E.;De Gonzalo-Calvo, Gonzalo;Gotor, V.:
From Lab Observation until the Development of a Complex Cooperative Redox Network: PIKAT Methodology. Comunicación en congreso. Multistep Enzyme-Catalyzed Processes 2012. Graz, Austria. 2012
Bisogno, F. R.;Rioz-martínez, A.;Rodríguez, C.;De Gonzalo-Calvo, Gonzalo;Lavandera, I.;Gotor, V.:
Enzymatic Cascades:Interconnected Redox Processes. Comunicación en congreso. XVIII Simposio Nacional de Química Orgánica. Córdoba, ARGENTINA. 2011
Lavandera, I.;Cuetos, A.;Rioz-martínez, A.;Bisogno, F. R.;Mautner, B.;Rodríguez, C.;De Gonzalo-Calvo, Gonzalo;Kroutil, W.;Gotor, V.:
Obtaining of ß-hydroxyesters through dynamic processes catalysed by alcohol dehydrogenases. Poster en Congreso. Biotrans 2011. GIARDINI DI NAXOS, ITALIA. 2011
Van Beek, H. L.;De Gonzalo-Calvo, Gonzalo;Fraaije, M. W.:
Using a thermostable Baeyer-Villiger monooxygenases for the creation of chimeric enzymes. Poster en Congreso. Biotrans 2011. GIARDINI DI NAXOS, ITALIA. 2011
Meeuwissen, S. A.;Rioz-martínez, A.;De Gonzalo-Calvo, Gonzalo;Fraaije, M. W.;Gotor, V.;Van Hest, J. C. M.:
Cofactor regeneration in polymersome nanoreactors: enzymatically catalysed Baeyer-Villiger reactions. Poster en Congreso. Biotrans 2011. GIARDINI DI NAXOS, ITALIA. 2011
De Gonzalo-Calvo, Gonzalo;Smit, C.;Jin, J.;Minnaard, A. J.;Fraaije, M. W.:
Creating a Flavoprotein Monooxygenase by Cofactor engineering. Poster en Congreso. NWO Study Group Meeting Design and Synthesis, Structure and Reactivity, Biochemistry. Lunteren, Holanda. 2010
De Gonzalo-Calvo, Gonzalo:
Biocatalysed concurrent production of enantioenriched compounds through parallel interconnected kinetic asymmetric transformations. Comunicación en congreso. COST Action CM0701 ¿CASCAT¿ Workshop-Conference. Vilnius, Lituania. 2010
De Gonzalo-Calvo, Gonzalo;Fraaije, M. W.;Rioz-martinez, A.;Martinez, D. E.;Kopacz, M.:
Biocatalyzed oxidations employing a fused FMO from Methylophaga sp. Comunicación en congreso. Biocat 2010. HAMBURGO, ALEMANIA. 2010
Lavandera, I.;Bisogno, F. R.;Rioz-martínez, A.;Rodríguez, C.;De Gonzalo-Calvo, Gonzalo;Gotor, V.:
I Taking advantage from the coupled cofactor recycling system in alcohol dehydrogenase-mediated protocols. Poster en Congreso. Biocat 2010. HAMBURGO, ALEMANIA. 2010
Rodríguez, C.;Torres-pazmiño, D. E.;De Gonzalo-Calvo, Gonzalo;Fraaije, M. W.:
Ionic liquid for enhancing enantioselectivity of phenylacetone monooxygenase from Thermobifida fusca. Poster en Congreso. Biocat 2010. HAMBURGO, ALEMANIA. 2010
Rioz-martínez, A.;Cuetos, A.;De Gonzalo-Calvo, Gonzalo;Fraaije, M. W.;Gotor, V.;Carriedo, G. A.;Valenzuela, M. L.:
Immobilization of Baeyer-Villiger monooxygenases (BVMOs) using polyphosphazenes as supports: Synthesis, catalytic activity and recycling efficiency. Poster en Congreso. Biocat 2010. HAMBURGO, ALEMANIA. 2010
Rioz-martínez, A.;De Gonzalo-Calvo, Gonzalo;Torres-pazmiño, D. E.;Fraaije, M. W.;Gotor, V.:
Synthesis of optically active sulfoxides by BVMOs as oxidative biocatalysts. Poster en Congreso. 8TH GREEN CHEMISTRY CONFERENCE. AN INTERNATIONAL EVENT. ZARAGOZA, España. 2009
Bisogno, F.r.;Rioz-martínez, A.;Rodríguez, C.;De Gonzalo-Calvo, Gonzalo;Lavandera, I.;Torres-pazmiño, D.e.;Fraaije, M.w.;Gotor, V.:
Parallel interconnected kinetic asymmetric transformations (PIKAT) applied to the concurrent chiral synthesis of sec-alcohols and sulfoxides. Poster en Congreso. BIOTRANS 2009. BERNA, SUIZA. 2009
Rodríguez, C.;De Gonzalo-Calvo, Gonzalo;Torres-pazmiño, D.e.;Fraaije, M.w.;Gotor, V.:
Isolated BVMO as biocatalyst in buffer-ionic liquid media. Poster en Congreso. BIOTRANS 2009. BERNA, SUIZA. 2009
De Freitas, D.e.;Vieria, G. A. B;De Oliveira, M. C. F.;De Mattos, M. C.;Lemos, T. L. G.;Melo, V. M. M.;De Gonzalo-Calvo, Gonzalo;Gotor-fernández, V.;Gotor, V.:
Chemoenzymatic synthesis of a natural biologically active naphthoquinone using lipases or alcohol dehydrogenases. Poster en Congreso. BIOTRANS 2009. BERNA, SUIZA. 2009
Rioz-martinez, A.;Bisogno, F.r.;Rodríguez, C.;De Gonzalo-Calvo, Gonzalo;Lavandera, I.;Torres-pazmiño, D.e.;Fraaije, M.w.;Gotor, V.:
Biocatalysed concurrent chiral synthesis through parallel interconnected kinetic asymmetric transformations. Poster en Congreso. BIOTRANS 2009. BERNA, SUIZA. 2009
Barros-fihlo, B.a.;Nunes, F. M.;De Oliveira, M. C. F.;De Mattos, M. C.;Lemos, T. L. G.;Melo, V. M. M.;De Gonzalo-Calvo, Gonzalo;Gotor-fernández, V.;Gotor, V.:
Filamentous fungi from the Brazilian biodiversity as biocatalyst in the reduction of prochiral ketones. Poster en Congreso. BIOTRANS 2009. BERNA, SUIZA. 2009
Machado, L.l.;Lemos, T.l.g.;De Mattos, M.c.;De Olivera, M.c.f.;De Gonzalo-Calvo, Gonzalo;Gotor-fernández, V.;Gotor, V.:
Enantioselective acetylation of heteroaryl alcohols by Manihot esculenta. Poster en Congreso. BIOTRANS 2009. BERNA, SUIZA. 2009
Lavandera, I.;De Gonzalo-Calvo, Gonzalo;Faber, K.;Kroutil, W.:
ADH-¿A¿ from Rhodococcus rubber catalyzes the reduction of ketones in nearly anhydrous media. Poster en Congreso. EUROPACAT VIII. FINLANDIA. 2007
Ottolina, G.;Carrea, G.;Zambianchi, F.;De Gonzalo-Calvo, Gonzalo;Fraaije, M.w.:
Enzymatic oxidations catalyzed by Baeyer-Villiger monooxygenases. Comunicación en congreso. BIOTRANS 2007. OVIEDO, ESPAÑA. 2007
Lavandera, I.;De Gonzalo-Calvo, Gonzalo;Durchschein, K.;Wurm, D.;Faber, K.:
Novel type of ionic liquids for efficient ketone reductions using ADH-¿A¿ from Rhodococcus rubber. Poster en Congreso. BIOTRANS 2007. OVIEDO, ESPAÑA. 2007
Torres-pazmiño, D.e.;De Gonzalo-Calvo, Gonzalo;Ottolina, G.;Carrea, G.;Janssen, D.b.;Fraaije, M.w.:
Exploring the biocatalytic potential of the novel thermostable Baeyer-Villiger monooxygenase: phenylacetone monooxygenase. Poster en Congreso. MULTISTEP ENZYME CATALYZED PROCESSES. GRAZ, AUSTRIA. 2006
Torres-pazmiño, D.e.;De Gonzalo-Calvo, Gonzalo;Ottolina, G.;Carrea, G.;Janssen, D.b.;Fraaije, M.w.:
Exploring the biocatalytic potential of the novel thermostable Baeyer-Villiger monooxygenase: phenylacetone monooxygenase. Poster en Congreso. 12TH EUROPEAN CONGRESS ON BIOTECHNOLOGY. COPENHAGUE, DINAMARCA. 2005
Torres-pazmiño, D.e.;De Gonzalo-Calvo, Gonzalo;Ottolina, G.;Carrea, G.;Janssen, D.b.;Fraaje, M.w.:
Exploring the biocatalytic potential of the novel thermostable Baeyer-Villiger: phenylacetone monooxygenase. Poster en Congreso. Biotrans 2005. DELFT (HOLANDA). 2005
Recuero, V.;Brieva, R.;De Gonzalo-Calvo, Gonzalo;Gotor, V.:
Chemoenzymatic preparation of optically pure isomers of aminochromanol and analogues. Poster en Congreso. Biotrans 2005. DELFT (HOLANDA). 2005
De Gonzalo-Calvo, Gonzalo;Ottolina, G.;Carrea, G.:
Baeyer-Villiger monooxygenases in organic solvents. Poster en Congreso. Biotrans 2005. DELFT (HOLANDA). 2005
De Gonzalo-Calvo, Gonzalo;Ottolina, G.;Carrea, G.;Fraaije, M.w.:
Formate/Organorhodium as flavin regeneration system in the enzymatic oxidation of sulfides and sulfoxides. Poster en Congreso. Biotrans 2005. DELFT (HOLANDA). 2005
De Gonzalo-Calvo, Gonzalo;Ottolina, G.;Fraaije, M.w.;Carrea, G.:
Oxidations catalyzed by a new thermophilic Baeyer-Villigerase. Poster en Congreso. COST D25 Applied Biocatalysis Workshop. Atenas (Grecia). 2004
De Gonzalo-Calvo, Gonzalo;Brieva, R.;Gotor, V.:
(R)-Oxynitrilase-catalyzed transformation of ¿-hydroxyaldehydes. Poster en Congreso. Biotrans 2001. DARMSTADT, Alemania. 2001
Rioz-martínez, A.;Cuetos, A.;Rodríguez, C.;De Gonzalo-Calvo, Gonzalo;Lavandera, I.;Fraaije, M. W.;Gotor, V.:
BVMO-catalysed oxidation of racemic ¿-alkyl-ß-ketoesters. Poster en Congreso. . .
De Gonzalo-Calvo, Gonzalo;Fernández-Fernández, Rosario;Lassaletta-Simon, Jose Mª:
Chitosan-supported ureas as organocatalysts in asymmetric synthesis. Comunicación en congreso. . .

Artículos publicados

Bisogno, Fabricio R.;Fernández-Fernández, Rosario;Lassaletta-Simon, Jose Mª;De Gonzalo-Calvo, Gonzalo:
Room Temperature Ionic Liquids in Asymmetric Hetero-Ene Type Reactions: Improving Organocatalyst Performance at Lower Temperatures. Molecules. 2021. Vol: 26. 10.3390/molecules26020355.
Aranda, Carmen;Oksdath-mansilla, Gabriela;Bisogno, Fabricio R.;de Gonzalo, Gonzalo:
Deracemisation Processes Employing Organocatalysis and Enzyme Catalysis. Advanced Synthesis & Catalysis. 2020. Vol: 362. Pág. 1233-1257. 10.1002/adsc.201901112.
de Gonzalo, Gonzalo;Martin, Caterina;Fraaije, Marco W.:
Positive Impact of Natural Deep Eutectic Solvents on the Biocatalytic Performance of 5-Hydroxymethyl-Furfural Oxidase. Catalysts. 2020. Vol: 10. 10.3390/catal10040447.
Aranda, Carmen;de Gonzalo, Gonzalo:
Biocatalyzed Redox Processes Employing Green Reaction Media. Molecules. 2020. Vol: 25. 10.3390/molecules25133016.
Domínguez-de María, Pablo;De Gonzalo-Calvo, Gonzalo;Alcántara, Andrés R.:
Biocatalysis as Useful Tool in Asymmetric Synthesis: An Assessment of Recently Granted Patents (2014¿2019). Catalysts. 2019. Vol: 9. doi:10.3390/catal9100802.
Gustafson, Karl P.;Bäckvall, Jan Erling;Görbe, Tamas;De Gonzalo-Calvo, Gonzalo;Yuan, Ning;Schreiber, Cynthia L.;Shchukarev, Andrey;Tai, Cheuk-wai;Zhou, Xiaodong;Persson, Ingmar:
Chemoenzymatic Dynamic Kinetic Resolution of primary benzylic amines using Pd(0)-CalB CLEA as a biohybrid catalyst. Chemistry: A European Journal. 2019. Vol: 25. Pág. 9174-9179. https://doi.org/10.1002/chem.201901418..
Willot, Sebastien J. P.;Tieves, Florien;Girhard, Marco;Urlacher, Vlada B.;Hollmann, Frank;De Gonzalo-Calvo, Gonzalo:
P450BM3-Catalyzed Oxidations Employing Dual Functional Small Molecules. Catalysts. 2019. Vol: 9.
De Gonzalo-Calvo, Gonzalo;Alcántara, Andrés R.;Domínguez-de María, Pablo:
Cyclopentyl Methyl Ether (CPME): A Versatile Eco-Friendly Solvent for Applications in Biotechnology and Biorefineries. ChemSusChem. 2019. Vol: 12. Pág. 2083-2097. 10.1002/cssc.201900079.
Domínguez-de María, Pablo;De Gonzalo-Calvo, Gonzalo:
Biocatalysis as Useful Tool in Asymmetric Synthesis: An Assessment of Recently Granted Patents (2014¿2019). Catalysts. 2019. Vol: 9. doi:10.3390/catal9100802.
Franconetti, Antonio;De Gonzalo-Calvo, Gonzalo:
Recent developments on supported hydrogen-bond organocatalysts. ChemCatChem. 2018. Vol: 10. Pág. 5554-5572. DOI: 10.1002/cctc.201801459.
Mourelle-insua, Ángela;De Gonzalo-Calvo, Gonzalo;Lavandera, Iván;Gotor-fernández, Vicente:
Stereoselective Enzymatic Reduction of 1,4-Diaryl-1,4-Diones to the Corresponding Diols Employing Alcohol Dehydrogenases. Catalysts. 2018. Vol: 8. 10.3390/catal8040150.
Franconetti, Antonio;Nuñez-franco, Reyes;De Gonzalo-Calvo, Gonzalo;Iglesias-Sigüenza, Javier;Alvarez-Gonzalez, Eleuterio;Cabrera-Escribano, Francisca:
Fingerprinting the Nature of Anions in Pyrylium Complexes: Dual Binding Mode for Anion-pi Interactions. Chemphyschem. 2018. Vol: 19. Pág. 327-334. 10.1002/ cphc.201700981.
De Gonzalo-Calvo, Gonzalo:
Lipase catalyzed kinetic resolution of racemic 1,2-diols containing a chiral quaternary center. Molecules. 2018. Vol: 23. 10.3390/molecules23071585.
De Gonzalo-Calvo, Gonzalo;Franconetti, Antonio;Fernández-Fernández, Rosario;Lassaletta-Simon, Jose Mª;Cabrera-Escribano, Francisca:
Preparation of chitosan-supported urea materials and their application in some organocatalytic procedures. Carbohydrate Polymers. 2018. Vol: 199. Pág. 365-374. 10.1016/j.carbpol.2018.07.009.
De Gonzalo-Calvo, Gonzalo;Franconetti, Antonio:
Enantioselective sulfoxidations employing the thermostable cyclohexanone monooxygenase from Thermocrispum municipale. Enzyme and Microbial Technology. 2018. Vol: 113. Pág. 24-28. 10.1016/j.enzmictec.2018.02.006.
De Gonzalo-Calvo, Gonzalo;Fürst, Maximilian;Fraaije , Marco:
Polycyclic Ketone Monooxygenase (PockeMO): A Robust Biocatalyst for the Synthesis of Optically Active Sulfoxides. Catalysts. 2017. Vol: 7. 10.3390/catal7100288.
Carmona, José Alberto;De Gonzalo-Calvo, Gonzalo;Serrano-Vallez, Inmaculada;Crespo-Peña, Ana María Del Rosario;Simek, Michal;Monge-Fernández, David;Fernández-Fernández, Rosario;Lassaletta-Simon, Jose Mª:
Asymmetric organocatalytic synthesis of tertiary azomethyl alcohols: key intermediates towards azoxy compounds and alpha-hydroxy-beta-amino esters. Organic and Biomolecular Chemistry. 2017. Vol: 15. Pág. 2993-3005. 10.1039/C7OB00308K.
Bisogno, Fabricio R.;López Vidal, Martín G.;De Gonzalo-Calvo, Gonzalo:
Organocatalysis and Biocatalysis Hand in Hand: Combining Catalysts in One-Pot Procedures. Advanced Synthesis & Catalysis. 2017. 10.1002/adsc.201700158.
Nguyen, Quoc-thai;De Gonzalo-Calvo, Gonzalo;Binda, Claudia;Rioz-martínez, Ana;Mattevi, Andrea;Fraaije, Marco W.:
Biocatalytic Properties and Structural Analysis of Eugenol Oxidase from Rhodococcus jostii RHA1: A Versatile Oxidative Biocatalyst. ChemBioChem. 2016. Vol: 17. Núm: 14. Pág. 1359-1366. 10.1002/cbic.201600148.
De Gonzalo-Calvo, Gonzalo:
Bacterial enzymes involved in lignin degradation. Journal of Biotechnology. 2016. Vol: 236. Pág. 110-119. http://doi.org/10.1016/j.jbiotec.2016.08.011.
Da Silva, Marcos R.;De Mattos, Marcos C.;Ferreira De Oliveira, M. De Conceicao;De Lemos, Telma L. G.;Ricardo, Nágila M. P. S.;De Gonzalo-Calvo, Gonzalo;Lavandera, Iván;Gotor-fernández, Vicente;Gotor, Vicente:
Asymmetric chemoenzymatic synthesis of N-acetyl-a-amino esters based on lipase-catalyzed kinetic resolutions through interesterification reactions. Tetrahedron. 2014. Vol: 70. Pág. 2264-2271. http://dx.doi.org/10.1016/j.tet.2014.02.012.
Da Silva, Marco R.;Montenegro, Tasso G. C.;De Mattos, Marcos C.;De Oliveira, Maria Da Conceicao F.;De Lemos, Telma L.g.;De Gonzalo-Calvo, Gonzalo;Lavandera, Iván;Gotor-fernández, Vicente;Gotor, Vicente:
Regioselective Preparation of Thiamphenicol Esters Through Lipase-Catalyzed Processes. Journal of the Brazilian Chemical Society. 2014. Vol: 25. Núm: 6. Pág. 987-994. 10.5935/0103-5053.20140069.
Riebel, A.;De Gonzalo-Calvo, Gonzalo;Fraaije, M.w.:
Expanding the biocatalytic toolbox of flavoprotein monooxygenases from Rhodococcus jostii RHA1. Journal of Molecular Catalysis B: Enzymatic. 2013. Vol: 88. Pág. 20-25.
De Gonzalo-Calvo, Gonzalo;Fraaije, Marco W.:
Recent developments in flavin-based catalysis. ChemCatChem. 2013. Vol: 5. Núm: 2. Pág. 403-415. 10.1002/cctc.201200466.
Van Beek, H.l.;De Gonzalo-Calvo, Gonzalo;Fraaije, M.w.:
Blending Baeyer-Villiger monooxygenases: using a robust BVMO as a scaffold for creating chimeric enzymes with novel catalytic properties. Chemical Communications. 2012. Vol: 48. Pág. 3288-3290.
Rodríguez, C.;De Gonzalo-Calvo, Gonzalo;Gotor, V.:
Optimization of oxidative bioconversions catalyzed by phenylacetone monooxygenase from Thermobifida fusca. Journal of Molecular Catalysis B: Enzymatic. 2012. Vol: 74. Pág. 138-143.
Dudek, H.m.;Riebel, A.;De Gonzalo-Calvo, Gonzalo;Stepniak, P.;Rychlewski, L.;Fraaije, M.w.:
Expanding the set of rhodococcal Baeyer-Villiger monooxygenases by high-throughput cloning, expression and substrate screening. Applied Microbiology and Biotechnology. 2012. Vol: 95. Pág. 1479-1489.
De Gonzalo-Calvo, Gonzalo;Orden, Alejandro A.;Bisogno, Fabricio R.:
New trends in organic synthesis with oxidative enzymes. Current Organic Chemistry. 2012. Vol: 16. Núm: 21. Pág. 2598-2612.
Mascotti, L.m.;Orden, A.a.;Bisogno, F.r.;De Gonzalo-Calvo, Gonzalo;Kurina-sanz, M.:
Aspergilus genes as source of new catalysts for sulfide oxidation. Journal of Molecular Catalysis B: Enzymatic. 2012. Vol: 82. Pág. 32-36.
De Gonzalo-Calvo, Gonzalo;Rodríguez, C.;Rioz-martínez, A.;Gotor, V.:
Improvement of the biocatalytic properties of one phenylacetone monooxygenase mutant in hydrophilic organic solvents. Enzyme and Microbial Technology. 2012. Vol: 50. Pág. 43-49.
Cuetos, Anibal;Rioz -martínez, Ana;Bisogno, Fabricio R.;Grischek, Barbara;Lavandera, Iván;De Gonzalo-Calvo, Gonzalo;Kroutil, Wolfgang;Gotor, Vicente:
Obtaining of enantiopure ¿-alkyl-ß-hydroxyesters through dynamic kinetic resolutions employing purified/overexpressed alcohol dehydrogenases. Advanced Synthesis & Catalysis. 2012. Vol: 354. Núm: 9. Pág. 1743-1749. 10.1002/adsc.201200139.
Cuetos, A.;Rioz-martínez, A.;Valenzuela, M.l.;Lavandera, I.;De Gonzalo-Calvo, Gonzalo;Carriedo, G.a.;Gotor, V.:
Immobilized redox enzymatic catalysts: Baeyer-Villiger monooxygenases supported on polyphosphazenes. Journal of Molecular Catalysis B: Enzymatic. 2012. Vol: 74. Pág. 178-183.
De Gonzalo-Calvo, Gonzalo;Smit, C.;Jin, J.;Minnaard, A.j.;Fraaije, M.w.:
Turning a riboflavin-binding protein into a self-sufficient monooxygenase by cofactor redesign¿. Chemical Communications. 2011. Vol: 47. Pág. 11050-11052.
Bizerra, A.m.c.;Montenegro, T.g.c.;Lemos, T.l.g.;De Oliveira, M.c.f.;De Mattos, M.c.;Lavandera, I.;Gotor, V.;De Gonzalo-Calvo, Gonzalo:
Enzymatic regioselective production of chloramphenicol esters. Tetrahedron. 2011. Vol: 67. Pág. 2858-2862.
Dudek, H.m.;Riebel, A.;De Gonzalo-Calvo, Gonzalo;Stepniak, P.;Wyrwicz, L.s.;Rychlewski, L.;Fraaije, M.w.:
Mapping the substrate binding site of phenylacetone monooxygenase from Thermobifida fusca by mutational analysis. Applied and Environmental Microbiology. 2011. Vol: 77. Pág. 5730-5738.
De Gonzalo-Calvo, Gonzalo;Lavandera, I.;Fraaije, M.w.;Gotor, V.:
Dynamic kinetic resolution of ¿-substituted ß-ketoesters catalysed by Baeyer-Villiger monooxygenases: Access to enantiopure ¿-hydroxy esters. Angewandte Chemie (International Edition). 2011. Vol: 50. Pág. 8387-8390.
Meewiseen, S.a.;Rioz-martínez, A.;De Gonzalo-Calvo, Gonzalo;Fraaije, M.w.;Gotor, V.;Van Hest, J.c.m.:
Cofactor regeneration in polymersome nanoreactors: enzymatically catalysed Baeyer-Villiger reactions. Journal of Materials Chemistry. 2011. Vol: 21. Pág. 18923-18926.
Rioz-martínez, A.;Kopacz, M.;De Gonzalo-Calvo, Gonzalo;Torres -pazmiño, D.e.;Gotor, V.;Fraaije, M.w.:
Exploring the biocatalytic scope of a bacterial flavin-containing monooxygenase. Organic and Biomolecular Chemistry. 2011. Vol: 9. Pág. 1337-1341.
Secundo, F.;Fiala, S.;Fraaije, M.w.;De Gonzalo-Calvo, Gonzalo;Melli, M.;Zambianchi, F.;Ottolina, G.:
Effects of water miscible organic solvents on the activity and conformation of the Baeyer-Villiger monooxygenases from Thermobifida fusca and Acinetob. Biotechnology and Bioengineering. 2011. Vol: 108. Pág. 491-499.
Bondani, Patricia;De Gonzalo-Calvo, Gonzalo;Andrade, Leandro H.;Fraaije, Marco W.:
Selective oxidations of organoboron compounds catalyzed by Baeyer-Villiger monooxygenases. Advanced Synthesis & Catalysis. 2011. Vol: 353. Núm: 11-12. Pág. 2169-2173. 10.1002/adsc.201100029.
De Gonzalo-Calvo, Gonzalo;Mihovilovic, Marko D.;Fraaije, Marco W.:
Recent developments in the application of Baeyer-Villiger monooxygenases as biocatalysts. ChemBioChem. 2010. Vol: 11. Núm: 16. Pág. 2208-2231. 10.1002/cbic.201000395.
Barros-fihlo, B.a.;Nunes, F.m.;De Oliveira, M.c.f.;Lemos, T.l.g.;De Mattos, M.c.;De Gonzalo-Calvo, Gonzalo;Gotor-fernández, V.;Gotor, V.:
Bioreduction of prochiral ketones by growing cells of Lasiodiplodia theobromae: Discovery of a versatile biocatalyst for asymmetric synthesis. Journal of Molecular Catalysis B: Enzymatic. 2010. Vol: 65. Pág. 37-40.
Dudek, H.m.;Torres -pamiño, D.e.;Rodríguez, C.;De Gonzalo-Calvo, Gonzalo;Gotor, V.;Fraaije, M.w.:
Investigating the coenzyme specificity of phenylacetone monooxygenase from Thermobifida fusca. Applied Microbiology and Biotechnology. 2010. Vol: 88. Pág. 1135-1143.
Rioz-martínez, A.;Bisogno, F.r.;Rodríguez, C.;De Gonzalo-Calvo, Gonzalo;Lavandera, I.;Torres -pazmiño, D.e.;Fraaije, M.w.;Gotor, V.:
Biocatalysed concurrent production of enantioenriched compounds through parallel interconnected kinetic asymmetric transformations. Organic and Biomolecular Chemistry. 2010. Vol: 8. Pág. 1431-1437.
Bisogno, Fabricio R.;Rioz -martínez, Ana;Rodríguez, Cristina;Lavandera, Iván;De Gonzalo-Calvo, Gonzalo;Torres-pazmiño, Daniel E.;Fraaije, Marco W.;Gotor, Vicente:
Oxidorreductases working together: Concurrent obtaining of valuable derivatives by employing PIKAT methodology. ChemCatChem. 2010. Vol: 2. Núm: 8. Pág. 946-949. 10.1002/cctc.201000115.
Bizerra, A.m.c.;De Gonzalo-Calvo, Gonzalo;Lavandera, I.;Gotor-fernández, V.;De Mattos, M.c.;De Oliveira, M.c.f.;Lemos, T.l.g.;Gotor, V.:
Reduction processes catalyzed by Vigna unguiculata. Tetrahedron: Asymmetry. 2010. Vol: 21. Pág. 566-570.
Rodríguez, C.;De Gonzalo-Calvo, Gonzalo;Fraaije, M.w.;Gotor, V.:
Ionic liquids for enhancing the enantioselectivity of isolated BVMO-catalysed oxidations. Green Chemistry. 2010. Vol: 12. Pág. 2255-2260.
Rodríguez, C.;De Gonzalo-Calvo, Gonzalo;Rioz-martínez, A.;Torres -pazmiño, D.e.;Fraaije, M.w.;Gotor, V.:
BVMO-catalysed dynamic kinetic resolution of racemic benzylketones in presence of anion exchange resins. Organic and Biomolecular Chemistry. 2010. Vol: 8. Pág. 1121-1125.
Rioz-martínez, A.;De Gonzalo-Calvo, Gonzalo;Torres -pazmiño, D.e.;Fraaije, M.w.;Gotor, V.:
Synthesis of 3-alkyl-3,4-dihydroisocoumarins by dynamic kinetic resolutions catalyzed by a Baeyer-Villiger monooxygenase. The Journal of Organic Chemistry. 2010. Vol: 75. Pág. 2073-2076.
Rioz-martínez, A.;De Gonzalo-Calvo, Gonzalo;Torres -pazmiño, D.e.;Fraaije, M.w.;Gotor, V.:
Enyzmatic synthesis of novel sulfoxides employing Baeyer-Villiger monooxygenases. European Journal Of Organic Chemistry. 2010. Pág. 6409-6416.
Rioz-martínez, A.;De Gonzalo-Calvo, Gonzalo;Gotor, V.:
Chemoenzymatic synthesis of substituted 1H-inden-1-ones using lipases. Synthesis. 2010. Pág. 110-114.
Vieira, G.a.b.;Lemos, T.l.g.;De Mattos, M.c.;De Oliveira, M.c.f.;De Gonzalo-Calvo, Gonzalo;Melo, V.m.m.;Gotor-fernández, V.;Gotor, V.:
Chemoenzymatic synthesis of optically active Mugetanol isomers: use of lipases and oxidorreductases in fragrance chemistry. Tetrahedron: Asymmetry. 2009. Vol: 20. Pág. 214-219.
Machado, L.l.;De Gonzalo-Calvo, Gonzalo;Lemos, T.l.g.;De Mattos, M.c.;De Oliveira, M.c.f.;Gotor -fernández, V.;Gotor, V.:
Enantioselective acetylation of racemic alcohols by Manihot esculenta and Passiflora edulis preparations. Journal of Molecular Catalysis B: Enzymatic. 2009. Vol: 60. Pág. 157-162.
Barros-fihlo, B.a.;De Oliveira, M.c.f.;Lemos, T.l.g.;De Mattos, M.c.;De Gonzalo-Calvo, Gonzalo;Gotor-fernández, V.;Gotor, V.:
Lentinus strigellus: a new versatile stereoselective biocatalyst for the bioreduction of prochiral ketones. Tetrahedron: Asymmetry. 2009. Vol: 20. Pág. 1057-1061.
De Freitas -araujo, D.m.;Vieira, G.a.b.;De Mattos, M.c.;Lemos, T.l.g.;De Oliveira, M.c.f.;Melo, V.m.m.;De Gonzalo-Calvo, Gonzalo;Gotor -fernández, V.;Gotor, V.:
Chemoenzymatic preparation of a biologically active naphthoquinone from Tabebuia impetiginosa using lipases or alcohol dehydrogenases. Journal of Molecular Catalysis B: Enzymatic. 2009. Vol: 61. Pág. 279-283.
Rodríguez, C.;De Gonzalo-Calvo, Gonzalo;Torres -pazmiño, D.e.;Fraaije, M.w.;Gotor, V.:
Baeyer-Villiger monooxygenase-catalyzed kinetic resolution of racemic ¿-alkyl benzyl ketones: enzymatic synthesis of chiral ¿-alkyl benzylketones and . Tetrahedron: Asymmetry. 2009. Vol: 20. Pág. 1168-1173.
Rioz-martínez, A.;De Gonzalo-Calvo, Gonzalo;Torres -pazmiño, D.e.;Fraaije, M.w.;Gotor, V.:
Enzymatic Baeyer-Villiger oxidation of benzofused ketones: Formation of regiocomplementary lactones. European Journal Of Organic Chemistry. 2009. Pág. 2532-2536.
Rodríguez, C.;De Gonzalo-Calvo, Gonzalo;Torres -pazmiño, D.e.;Fraaije, M.w.;Gotor, V.:
Selective Baeyer-Villiger oxidation of racemic ketones in aqueous-organic media catalyzed by phenylacetone monooxygenase. Tetrahedron: Asymmetry. 2008. Vol: 19. Pág. 197-203.
Machado, L.l.;Monte, F.j.q.;De Oliveira, M.c.f.;De Mattos, M.c.;De Gonzalo-Calvo, Gonzalo;Gotor-fernández, V.;Gotor, V.;Lemos, T.l.g.:
Bioreduction of aromatic aldehydes and ketones by fruits¿ barks of Passiflora edulis. Journal of Molecular Catalysis B: Enzymatic. 2008. Vol: 54. Pág. 103-106.
Machado, L.l.;Lemos, T.l.g.;De Mattos, M.c.;De Oliveira, M.c.f.;De Gonzalo-Calvo, Gonzalo;Gotor -fernández, V.;Gotor, V.:
Immobilized Manihot esculenta preparation as novel biocatalyst in the acetylation of racemic alcohols. Tetrahedron: Asymmetry. 2008. Vol: 19. Pág. 1418-1423.
Zambianchi, F.;Fraaije, M.w.;Carrea, G.;De Gonzalo-Calvo, Gonzalo;Rodríguez, C.;Gotor, V.;Ottolina, G.:
Titration and assignment of residues that regulate the enantioselectivity of phenylacetone monooxygenase. Advanced Synthesis & Catalysis. 2007. Vol: 349. Pág. 1327-1331.
Rodríguez, C.;De Gonzalo-Calvo, Gonzalo;Fraaije, M.w.;Gotor, V.:
Enzymatic kinetic resolution of racemic ketones catalyzed by Baeyer-Villiger monooxygenases. Tetrahedron: Asymmetry. 2007. Vol: 18. Pág. 1338-1344.
De Gonzalo-Calvo, Gonzalo;Lavandera, I.;Durchschein, K.;Wurm, D.;Faber, K.;Kroutil, W.:
Asymmetric biocatalytic reduction of ketones using hydroxyl-functionalised water-miscible ionic liquids as solvents. Tetrahedron: Asymmetry. 2007. Vol: 18. Pág. 2541-2546.
Recuero, V.;De Gonzalo-Calvo, Gonzalo;Brieva, R.;Gotor, V.:
Chemoenzymatic preparation of enantiopure isomers of 4-aminochroman-3-ol and 1-amino-1,2,3,4-tetrahydronaphthalen-2-ol. European Journal Of Organic Chemistry. 2006. Pág. 4224-4230.
De Gonzalo-Calvo, Gonzalo;Ottolina, G.;Zambianchi, F.;Fraaije, M.w.;Carrea, G.:
Biocatalytic properties of Baeyer-Villiger monooxygenases in aqueous-organic media. Journal of Molecular Catalysis B: Enzymatic. 2006. Vol: 39. Pág. 91-97.
De Gonzalo-Calvo, Gonzalo;Torres -pazmino, D.e.;Ottolina, G.;Fraaije, M.w.;Carrea, G.:
4-Hydroxyacetophenone monooxygenase from Pseudomonas fluorescens ACB as an oxidative biocatalyst in the synthesis of optically active sulfoxides. Tetrahedron: Asymmetry. 2006. Vol: 17. Pág. 130-135.
Rodríguez, C.;De Gonzalo-Calvo, Gonzalo;Torres -pazmiño, D.e.;Fraaije, M.w.;Gotor, V.:
Baeyer-Villiger monooxygenase-catalyzed kinetic resolution of racemic ¿-alkyl benzyl ketones: enzymatic synthesis of chiral ¿-alkyl benzylketones and . Tetrahedron: Asymmetry. 2005. Vol: 20. Pág. 1168-1173.
Ottolina, G.;De Gonzalo-Calvo, Gonzalo;Carrea, G.;Danieli, B.:
Enzymatic Baeyer-Villiger oxidation of bicyclic diketones. Advanced Synthesis & Catalysis. 2005. Vol: 347. Pág. 1035-1040.
Ottolina, G.;De Gonzalo-Calvo, Gonzalo;Carrea, G.:
Theoretical studies of oxygen atom transfer from flavin to electron-rich substrates. Journal of Molecular Structure. 2005. Vol: 757. Pág. 175-181.
De Gonzalo-Calvo, Gonzalo;Torres -pazmino, D.e.;Ottolina, G.;Fraaije, M.w.;Carrea, G.:
Oxidations catalyzed by phenylacetone monooxygenase from Thermobifida fusca. Tetrahedron: Asymmetry. 2005. Vol: 16. Pág. 3077-3083.
De Gonzalo-Calvo, Gonzalo;Ottolina, G.;Carrea, G.;Fraaije, M.w.:
¿[Cp*Rh (bpy)(H2O)]2+ as coenzyme substitute in enzymatic oxidations catalyzed by Baeyer-Villiger monooxygenases. Chemical Communications. 2005. Pág. 3724-3726.
Levy, L.m.;De Gonzalo-Calvo, Gonzalo;Gotor, V.:
Resolution of free and N-protected 3-aminocyclohexanols via lipase-catalyzed enantioselective acylation in organic media. Tetrahedron: Asymmetry. 2004. Vol: 15. Pág. 2051-2056.
De Gonzalo-Calvo, Gonzalo;Lavandera, I.;Brieva, R.;Gotor, V.:
Enzymatic acylation reactions on ¿-hydroxycyanohydrins. Tetrahedron. 2004. Vol: 60. Pág. 10525-10532.
De Gonzalo-Calvo, Gonzalo;Brieva, R.;Sánchez, V.m.;Bayod, M.;Gotor, V.:
Enzymatic alkoxycarbonylation reactions on the intermediate in the synthesis of (-)-paroxetine, trans-N-benzyloxycarbonyl-4-(4¿-fluorophenyl)-3-hydrox. Tetrahedron: Asymmetry. 2003. Vol: 14. Pág. 1725-1731.
De Gonzalo-Calvo, Gonzalo;Brieva, R.;Sánchez, V.m.;Bayod, M.;Gotor, V.:
Anhydrides as acylating agents in the enzymatic resolution of an intermediate of (-)-paroxetine. The Journal of Organic Chemistry. 2003. Vol: 68. Pág. 3333-3336.
De Gonzalo-Calvo, Gonzalo;Brieva, R.;Gotor, V.:
(R)-Oxynitrilase-catalyzed transformation of ¿-hydroxyalakanals. Journal of Molecular Catalysis B: Enzymatic. 2002. Vol: 19-20. Pág. 223-230.
De Gonzalo-Calvo, Gonzalo;Brieva, R.;Sánchez, V.m.;Bayod, M.;Gotor, V.:
Enzymatic resolution of trans-4-(4¿-fluorophenyl)-3-hydroxymethylpiperidines, key intermediates in the synthesis of (-)-Paroxetine. The Journal of Organic Chemistry. 2001. Vol: 66. Pág. 8947-8953.

Tesis dirigidas o codirigidas

Rioz-martínez, Ana:
Aplicación de flavoenzimas en síntesis orgánica. Tesis Doctoral. 2012
Rodríguez, Cristina:
Uso de nuevas Baeyer-Villiger monooxigenasas como biocatalizadores en la síntesis de compuestos oxigenados ópticamente activos. Tesis Doctoral. 2010