FRANCISCO MANUEL VEGA MORENO

Categoría
Profesor Titular de Universidad

Contacto

Correo electrónico

Departamento

Área
Biología Celular

Investigación

Grupo de investigación

FISIOPATOLOGÍA DE CÉLULAS MADRE NEURALES (CBSCS)

Proyectos y contratos de investigación

Ayuda de Divulgación científica 2020 (Participante)
Jornada sobre Alergia e Intolerancias alimentarias frecuentes en la población infantil (Participante)
Ayuda para actividades de Divulgación científica (Participante)
Identification of Regulators of breast cancer cell invasion and migration [Grant 2008MayPR13] (2008MayPR13 - Investigador/a)
Marie Curie Individual Research contract (Investigador/a)

Capítulos en Libros

Francisco M Vega;Reymond, Nicolas;Ridley, Anne:
RhoC. Pág. 1664-1668. Springer. Springer. 2018.
Vega-Moreno, Francisco Manuel;Reymond, Nicolas;Ridley, Anne J.:
RhoC. Pág. 1664-1668. 2012.
Vega-Moreno, Francisco Manuel:
VRK1:vaccinia-related kinase 1. Pág. 1992-1996. 2012.

Asistencia a congresos

Vega-Moreno, Francisco Manuel;Ridley, Anne J.:
Rho subfamily GTPases have distinct roles in migration and invasion by acting through different targets. Poster en Congreso. Frontiers in Cell Migration. BETHESDA, EE.UU. 2011
Vega-Moreno, Francisco Manuel:
Rho subfamily GTPases have distinct roles in migration and invasion by acting through different targets. Conferencia Congreso no publicada. Actin 2010 UK Meeting. BRISTOL , REINO UNIDO. 2010
Vega-Moreno, Francisco Manuel;Ridley, Anne J.:
Rho GTPases isoforms specificity in tumor cell migration and invasion. Poster en Congreso. Beatson International Cancer Conference: Microenviroment, Motility and Metastasis. GLASGOW - REINO UNIDO. 2009
Vega-Moreno, Francisco Manuel;Ridley, Anne J.:
Investigating the roles of Rho isoforms in tumor cell invasion and migration . Poster en Congreso. Keystone Symposia: Cell Migration in Invasion and Inflammation. TAOS, NEW MEXICO (EEUU). 2008
Vega-Moreno, Francisco Manuel:
Rho GTPases isoforms specificity in tumor cell migration and invasion. Conferencia Congreso no publicada. III Meeting in Cell Proliferation and Cancer. MALLORCA, ESPAÑA. 2008
Vega-Moreno, Francisco Manuel;Ridley, Anne J.:
Gene silencing technology for the study of Rho GTPases in tumor cell invasion and migration. Poster en Congreso. Gordon Research Conference: Mechanisms of Cell Signalling. . 2007
Vega-Moreno, Francisco Manuel;Ridley, Anne J.:
Gene silencing technology for the study of Rho GTPases in tumor cell invasion. Poster en Congreso. EMBO Worshop in Cell Migration, Tissue Invasion and Disease. CAPRI (ITALIA). 2006
Vega-Moreno, Francisco Manuel:
Gene silencing technology for the study of Rho GTPases in tumor cell invasion. Conferencia Congreso no publicada. Actin 2006 UK meeting. BRISTOL , REINO UNIDO. 2006
Vega-Moreno, Francisco Manuel:
The human kinase VRK1 and its role in the regulation of p53 tumor suppressor. Conferencia Congreso no publicada. XXVIII Congreso de la Sociedad española de Bioquimica y Biología Molecular (SEBBM). . 2005
Vega-Moreno, Francisco Manuel;Lazo, Pedro A.:
p53 phosphorylation by the human vaccinia-related kinase 1 (VRK1). Poster en Congreso. International p53 workshop. . 2002

Artículos publicados

Colmenero-Repiso, Ana;Gómez, María De Los Ángeles;RODRIGUEZ-PRIETO, ISMAEL;Rivas-Infante, Eloy;Pardal-Redondo, Ricardo;Francisco M Vega:
Identification of VRK1 as a New Neuroblastoma Tumor Progression Marker Regulating Cell Proliferation. Cancers. 2020. Vol: 12. Núm: 11.
Francisco M Vega;Pardal-Redondo, Ricardo;Colmenero-Repiso, Ana;Gómez, María De Los Ángeles;RODRIGUEZ-PRIETO, ISMAEL;Ramirez-Villar, Gema Lucia;Marquez-Vega, Catalina;Cabello-Laureano, Rosa María:
CD44-high Neural Crest Stem-Like Cells Are Associated With Tumour Aggressiveness and Poor Survival in Neuroblastoma Tumours. EBioMedicine. 2019. Vol: 49. Pág. 82-95. 10.1016/j.ebiom.2020.102668.
Huertas, Carlos;Gómez, María De Los Ángeles;Pardal-Redondo, Ricardo;Francisco M Vega:
Hypoxia in the Initiation and Progression of Neuroblastoma Tumours. International Journal of Molecular Sciences. 2019. Vol: 21. Núm: 1. Pág. 39-53.
Linares-Clemente, Pedro;Mora, Jaume;Cabello-Laureano, Rosa María;Marquez-Vega, Catalina;Rivas-Infante, Eloy;Pardal-Redondo, Ricardo;RODRIGUEZ-PRIETO, ISMAEL;Ramirez-Villar, Gema Lucia;De Torres, Carolina;Santamaria, Vicente;Pascual-vaca, Diego;Colmenero-Repiso, Ana;Francisco M Vega:
Neural crest derived progenitor cells contribute to tumor stroma and aggressiveness in high-risk neuroblastoma . Oncotarget. 2017. Vol: 8. Núm: 52. Pág. 89775-89792.
Vega-Moreno, Francisco Manuel;Bolivar-Perez, Jorge;Pardal-Redondo, Ricardo;Garcia-Cozar, Francisco Jose;Aguado-Vidal, Enrique;Heck, Albert J.r. ;Duran-Ruiz, Mª Carmen;Gautier, Violette;Fernandez-Ponce, Cecilia;Extremera, Maria Jesus;Altelaar, A.f.m.;Millan, Jaime;Tellez, Juan C.;Hernandez-campos, Jose A;Conejero, Rosario:
The atheroma plaque secretome stimulates the mobilization of endothelial progenitor cells ex vivo. Journal of Molecular and Cellular Cardiology. 2017. Vol: 105. Pág. 12-23. 10.1016/j.yjmcc.2017.02.001.
Francisco M Vega;Ridley, Anne J.:
The RhoB small GTPase in physiology and disease. Small GTPases. 2016. Vol: Nov 2. Pág. 1-10. 10.1080/21541248.2016.1253528.
Erdreich-epstein, Anat;Campan, Mihaela;Morales, Guillermo;Garlich, Joseph R.;Laird, Peter W. ;Seeger, Robert C. ;Shimada, Hiroyuki ;Durden, Donald L.;Singh, Alok R.;Joshi, Shweta ;Francisco M Vega;Guo, Pinzheng;Xu, Jingying;Groshen, Susan;Ye, Wei;Millard, Melissa:
Association of high microvessel ¿vß3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibi. Oncotarget. 2016. Vol: Nov 16. 10.18632/oncotarget.13386.
Moura, David S.;Fernandez, Isabel F.;Marín-royo, Gema;López-sánchez, Inmaculada;Martín-doncel, Elena;Francisco M Vega;Lazo-zbikowsqui, Pedro A.:
Oncogenic Sox2 regulates and cooperates with VRK1 in cell cycle progression and differentiation. Scientific Reports. 2016. Vol: 6. 10.1038/srep28532.
Francisco M Vega;Reymond, Nicolas;Thomas, Marian;Ridley, Anne J.:
The Rho GTPase RhoB regulates cadherin expression and epithelial cell-cell interaction . Cell Communication and Signaling [electronic resource]. 2015. Vol: 13. Núm: 6.
Mártinez-criado, Yolanda;Cabella, Rosa;Fernández-pineda, Israel;Vega, F.M.:
Study of the expression of neural stem cell markers in neuroblastoma tumor samples and correlation with prognostic factors. Cirugía Pediátrica. 2013. Vol: 3. Pág. 112-118.
Vega-Moreno, Francisco Manuel;Colomba, Audrey;Reymond, Nicolas;Thomas, Mairian;Ridley, Anne J.:
RhoB regulates cell migration through altered focal adhesion dynamics. Open Biology. 2012. Vol: 2. Núm: 5. 10.1186/s12964-015-0085-y.
Reymond, Nicolas;Ridley, Anne J.;Vega-Moreno, Francisco Manuel:
Cdc42 promotes transendothelial migration of cancer cells through BETA1 integrin. Journal of Cell Biology. 2012. Vol: 199. Núm: 4. Pág. 653-668.
Vega-Moreno, Francisco Manuel;Fruhwirth, G.;Ng, Tony;Ridley, Anne J.:
RhoA and RhoC have distinct roles in migration and invasion by acting through different targets. Journal of Cell Biology. 2011. Vol: 193. Núm: 4. Pág. 655-665.
Valbuena, Alberto;Sanz-garcía, Marta;López-sánchez, I.;Vega-Moreno, Francisco Manuel;Lazo, Pedro A.:
Roles of VRK1 as a new player in the control of biological processes required for cell division. Cellular Signalling. 2010. Vol: 23. Núm: 8. Pág. 1267-1272.
Valbuena, Alberto;Blanco, Sandra;Vega-Moreno, Francisco Manuel;Lazo, Pedro A.:
The C/H3 domain of p300 is required to protect VRK1 and VRK2 from their downregulation induced by p53. PLoS ONE. 2008. Vol: 3. Núm: 7.
Durán, María Del Carmen;Vega-Moreno, Francisco Manuel;Moreno-bueno, G.;Artiga, M.j.;Sánchez, L.;Palacios-Calvo, José;Ridley, Anne J.;Timms, J.f.:
Characterisation of tumoral markers correlated with ErbB2 (HER2/Neu) overexpression and metastasis in breast cancer. Proteomics. Clinical Applications. 2008. Vol: 2. Pág. 1313-1326.
Vega-Moreno, Francisco Manuel;Ridley, Anne J.:
Rho GTPases in cancer cell biology. FEBS Letters. 2008. Vol: 582. Núm: 14. Pág. 2093-2101.
Valbuena, Alberto;Lopez-sanchez, I.;Vega-Moreno, Francisco Manuel;Sevilla, Ana;Sanz-garcía, Marta;Blanco, Sandra;Lazo, Pedro A.:
Identification of a human epitope in human vaccinia-related kinase 1 (VRK1) and detection of different intracellular subpopulations. Archives of Biochemistry and Biophysics. 2007. Vol: 465. Núm: 1. Pág. 219-226.
Vega-Moreno, Francisco Manuel;Ridley, Anne J.:
Snapshot: Rho family GTPases. Cell. 2007. Vol: 129. Núm: 7. Pág. 1430-1431.
Wheeler, A.p.;Wells, C.;Smith, S.d.;Vega-Moreno, Francisco Manuel;Herderson, R.b.;Tybulewicz, V.l.;Ridley, Anne J.:
Rac1 and Rac2 regulate macrophage morphology but are not essential for migration. Journal of Cell Science. 2006. Vol: 19. Núm: 13. Pág. 2749-2757.
Blanco, Sandra;Klimcakova, L.;Vega-Moreno, Francisco Manuel;Lazo, Pedro A.:
Subcellular localization of vaccinia-related kinase 2 (VRK2) isoforms determines their different effects on p53 stability in tumour cell lines. The FEBS Journal. 2006. Vol: 273. Núm: 1. Pág. 2487-2504.
Santos, Claudio R.;De Alava, Enrique;Sanchez-cespedes, M.;Lazo, Pedro A.;Rodriguez-pinilla, M.;Vega-Moreno, Francisco Manuel;Rodriguez-peralto, J.l.;Blanco, Sandra;Sevilla, Ana;Valbuena, Alberto;Hernandez, T.;Van Wijnen, A.j.:
VRK1 Signaling pathway in the context of the proliferation phenotype in Head and Neck squamous cell carcinoma. Molecular Cancer Research. 2006. Vol: 4. Núm: 3. Pág. 177-185.
Valbuena, Alberto;Vega-Moreno, Francisco Manuel;Lazo, Pedro A.:
p53 downregulates its activating vaccinia-related kinase 1 (VRK1) forming a new autoregulatory loop. Molecular and Cellular Biology. 2006. Vol: 26. Núm: 13. Pág. 4782-4793.
Vega-Moreno, Francisco Manuel;Sevilla, Ana;Lazo, Pedro A.:
p53 Stabilization and accumulation induced by human vaccinia-related kinase 1. Molecular and Cellular Biology. 2004. Vol: 24. Núm: 23. Pág. 10366-10380.
Santos, Claudio R.;Vega-Moreno, Francisco Manuel;Blanco, Sandra;Barcia, Ramón;Lazo, Pedro A.:
The vaccinia virus B1R kinase induces p53 downregulation by and Mdm2-dependent mechanism. Virology. 2004. Vol: 328. Núm: 2. Pág. 254-265.
Sevilla, Ana;Santos, Claudio R.;Barcia, Ramón;Vega-Moreno, Francisco Manuel;Lazo, Pedro A.:
c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK). Oncogene. 2004. Vol: 23. Núm: 55. Pág. 8950-8958.
Sevilla, Ana;Santos, Claudio R.;Vega-Moreno, Francisco Manuel;Lazo, Pedro A.:
Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with J. Journal of Biological Chemistry. 2004. Vol: 279. Núm: 26. Pág. 27458-27465.
Vega-Moreno, Francisco Manuel;Gonzalo, P.;Gaspar, Maria Luisa;Lazo, Pedro A.:
Expression of the VRK (vaccinia-related kinase) gene family of p53 regulators in murine hematopoietic development. FEBS Letters. 2003. Vol: 544. Pág. 176-180.
Barcia, Ramón;Lopez-borges, Susana;Vega-Moreno, Francisco Manuel;Lazo, Pedro A.:
Kinetic properties of p53 phosphorylation by the human vaccinia-related kinase 1. Archives of Biochemistry and Biophysics. 2002. Vol: 399. Pág. 1-5.
Martín-Rubio, María Esther;Hidalgo-Jimenez, Josefina;Vega-Moreno, Francisco Manuel;Velasco-Lopez, Angel:
Trimeric G proteins modulate the dynamic interaction of PKAII with the Golgi complex. Journal of Cell Science. 1999. Vol: 112. Núm: 22. Pág. 3869-3878.

Tesis dirigidas o codirigidas

Colmenero-Repiso, Ana:
Papel de la quinasa humana VRK1 en la biología del neuroblastoma. Tesis Doctoral. 2020