DIANA AGUILAR MORANTE

Investigación

Grupo de investigación

FISIOPATOLOGÍA DE CÉLULAS MADRE NEURALES (CBSCS)

Proyectos y contratos de investigación

Ayuda Suplementaria a Grupos de Investigación Por Captación de Fondos. Modalidad A (VIIPPIT-2023-I.4 - Responsable)
PROGRAMA DE AYUDAS PARA ASISTENCIA Y PARTICIPACIÓN EN CONGRESOS CIENTÍFICOS DE CARÁCTER INTERNACIONAL. III.4. (1800009999 - Responsable)
Fight against therapeutic resistance in Glioblastoma tumours using genomic instability as ally (EMERGIA Program_EMC21_00385 - Investigador Principal Joven)
Unravelling functional interplay between R-loops and Replication-Transcription Conflicts as a novel therapeutic target in High-Risk neuroblastoma tumo (Ayudas Investigador AECC 2022-INVES222818AGUI - Responsable)
Fight against therapeutic resistance in High-Risk Neuroblastoma using genomic instability as ally (CSyF-2022-Proy24664. Ref:PI-0034-2022 - Investigador Principal Joven)
Identificación de nuevas dianas y potenciales agentes terapéuticos dirigidos contra las células madre cancerosas en el tratamiento del neuroblastoma p (RH-0036-2020 - Responsable)
Fisiopatología de Células Madre Derivadas de la Cresta Neural (SAF2016-80412-P - Investigador/a)
Fisiopatología de Células Madre Derivadas de la Cresta Neural (SAF2013-48535-P - Investigador/a)

Asistencia a congresos

Aguilar -Morante, Diana:
Presentación oral. Ponencia en Congreso. British Neuro-Oncology Society Annual Meeting. - Manchester, Reino Unido. 2023

Artículos publicados

Aguilar -Morante, Diana:
Analysis of serial neuroblastoma PDX passages in mice allows the identification of new mediators of neuroblastoma aggressiveness. International Journal of Molecular Sciences. 2023. Vol: 24. Núm: 2. 10.3390/ijms24021590.
Aguilar -Morante, Diana:
Therapeutic Opportunities of Disrupting Genome Integrity in Adult Diffuse Glioma. Biomedicines. 2022. Vol: 10. Núm: 2. 10.3390/biomedicines10020332.
Aguilar -Morante, Diana:
CtIP-dependent nascent RNA expression flanking DNA breaks guides the choice of DNA repair pathway. Nature Communications. 2022. 10.1038/s41467-022-33027-z.
Aguilar -Morante, Diana:
A high-affinity peptide ligand targeting syntenin inhibits glioblastoma . Journal of Medicinal Chemistry. 2021. Vol: 64. Núm: 3. Pág. 1423-1434. 10.1021/acs.jmedchem.0c00382.
Aguilar -Morante, Diana:
SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells. Nature Communications. 2020. Vol: 11. 10.1038/s41467-020-18549-8.
Aguilar -Morante, Diana:
CD44-high Neural Crest Stem-Like Cells Are Associated With Tumour Aggressiveness and Poor Survival in Neuroblastoma Tumours. EBioMedicine. 2019. Vol: 49. Pág. 82-95. 10.1016/j.ebiom.2020.102668.
Linares-Clemente, Pedro;Mora, Jaume;Cabello-Laureano, Rosa María;Marquez-Vega, Catalina;Rivas-Infante, Eloy;Pardal-Redondo, Ricardo;Aguilar -Morante, Diana;RODRIGUEZ-PRIETO, ISMAEL;Ramirez-Villar, Gema Lucia;De Torres, Carolina;Santamaria, Vicente;Pascual-vaca, Diego;Colmenero-Repiso, Ana;Francisco M Vega:
Neural crest derived progenitor cells contribute to tumor stroma and aggressiveness in high-risk neuroblastoma . Oncotarget. 2017. Vol: 8. Núm: 52. Pág. 89775-89792. 10.18632/oncotarget.21128.
Aguilar -Morante, Diana:
CCAAT/Enhancer binding protein silencing mitigates glial activation and neurodegeration in a rat model of Parkinson¿s disease. Scientific Reports. 2017. Vol: 7. 10.1038/s41598-017-13269-4.
Aguilar -Morante, Diana:
Complement component 3 (C3) expression after excitotoxic injury: Role of C/EBPß. Journal of Neuroinflammation. 2016. Vol: 13(1). Núm: 276. 10.1186/s12974-016-0742-0 .
Aguilar -Morante, Diana:
CCAAT/Enhancer binding protein beta directly regulates the expression of the complement component 3 gene in neural cells: implications for the proinfl. Journal of Neuroinflammation. 2015. Vol: 12. Núm: 14. 10.1186/s12974-014-0223-2.
Aguilar -Morante, Diana:
CCAAT/Enhancer Binding protein beta induces motility and invasion of glioblastoma cells through transcriptional regulation of the calcium binding prot. Oncotarget. 2015. Vol: 6. Núm: 6. Pág. 4369-4384. 10.18632/oncotarget.2976.
Aguilar -Morante, Diana:
Silencing phosphodiesterase 7B gene by lentiviral-shRNA interference attenuates neurodegeneration and motor deficits in hemiparkinsonian mice. Neurobiology of Aging. 2015. Vol: 36. Núm: 2. Pág. 1160-1173. http://dx.doi.org/10.1016/j.neurobiolaging.2014.10.008.
Aguilar -Morante, Diana:
The new iminothiadiazole derivative VP1.14 ameliorates hippocampal damage after an excitotoxic injury. Journal of Neurochemistry. 2012. Vol: 122. Núm: 6. Pág. 1193-1202. 10.1111/j.1471-4159.2012.07866.x.
Aguilar -Morante, Diana:
Role of C/EBPß transcription factor in adult hippocampal neurogenesis. PLoS One. 2011. Vol: 6. Núm: 10.
Aguilar -Morante, Diana:
Decreased CCAAT/enhancer binding protein beta expression inhibits the growth of glioblastoma cells. Neuroscience. 2011. Vol: 176. Pág. 110-119. 10.1016/j.neuroscience.2010. 12.025.
Aguilar -Morante, Diana:
. Inhibition of Glioblastoma Growth by the Thiadiazolidinone Compound TDZD-8. PLoS One. 2010. Vol: 5. Núm: (11). 10.1371/journal.pone.0013879.
Aguilar -Morante, Diana:
Cancer stem cells and brain tumors. Clinical & Translational Oncology. 2008. Vol: 10. Núm: 5. Pág. 262-267.

Tesis dirigidas o codirigidas

(Doctorando no grabado):
Papel del Componente 3 del Complemento (C3) como mediador de C/EBPß en los procesos inflamatorios y excitotóxicos del Sistema Nervioso Central.. Tesis Doctoral. 2014