Directorio
FRANCISCO MANUEL VEGA MORENO
Categoría
Profesor Titular de Universidad
Contacto
Correo electrónico
Departamento
Área
Biología Celular
Docencia
Investigación
Grupo de investigación
FISIOPATOLOGÍA DE CÉLULAS MADRE NEURALES (CBSCS)
Proyectos y contratos de investigación
Ayuda de Divulgación científica 2020 (Participante)
Jornada sobre Alergia e Intolerancias alimentarias frecuentes en la población infantil (Participante)
Ayuda para actividades de Divulgación científica (Participante)
Identification of Regulators of breast cancer cell invasion and migration [Grant 2008MayPR13] (2008MayPR13 - Investigador/a)
Marie Curie Individual Research contract (Investigador/a)
Capítulos en Libros
Francisco M Vega;Reymond, Nicolas;Ridley, Anne:
RhoC. Pág. 1664-1668. Springer. Springer. 2018.
RhoC. Pág. 1664-1668. Springer. Springer. 2018.
Vega-Moreno, Francisco Manuel:
VRK1:vaccinia-related kinase 1. Pág. 1992-1996. 2012.
VRK1:vaccinia-related kinase 1. Pág. 1992-1996. 2012.
Vega-Moreno, Francisco Manuel;Reymond, Nicolas;Ridley, Anne J.:
RhoC. Pág. 1664-1668. 2012.
RhoC. Pág. 1664-1668. 2012.
Asistencia a congresos
Vega-Moreno, Francisco Manuel;Ridley, Anne J.:
Rho subfamily GTPases have distinct roles in migration and invasion by acting through different targets. Poster en Congreso. Frontiers in Cell Migration. BETHESDA, EE.UU. 2011
Rho subfamily GTPases have distinct roles in migration and invasion by acting through different targets. Poster en Congreso. Frontiers in Cell Migration. BETHESDA, EE.UU. 2011
Vega-Moreno, Francisco Manuel:
Rho subfamily GTPases have distinct roles in migration and invasion by acting through different targets. Conferencia Congreso no publicada. Actin 2010 UK Meeting. BRISTOL , REINO UNIDO. 2010
Rho subfamily GTPases have distinct roles in migration and invasion by acting through different targets. Conferencia Congreso no publicada. Actin 2010 UK Meeting. BRISTOL , REINO UNIDO. 2010
Vega-Moreno, Francisco Manuel;Ridley, Anne J.:
Rho GTPases isoforms specificity in tumor cell migration and invasion. Poster en Congreso. Beatson International Cancer Conference: Microenviroment, Motility and Metastasis. GLASGOW - REINO UNIDO. 2009
Rho GTPases isoforms specificity in tumor cell migration and invasion. Poster en Congreso. Beatson International Cancer Conference: Microenviroment, Motility and Metastasis. GLASGOW - REINO UNIDO. 2009
Vega-Moreno, Francisco Manuel;Ridley, Anne J.:
Investigating the roles of Rho isoforms in tumor cell invasion and migration . Poster en Congreso. Keystone Symposia: Cell Migration in Invasion and Inflammation. TAOS, NEW MEXICO (EEUU). 2008
Investigating the roles of Rho isoforms in tumor cell invasion and migration . Poster en Congreso. Keystone Symposia: Cell Migration in Invasion and Inflammation. TAOS, NEW MEXICO (EEUU). 2008
Vega-Moreno, Francisco Manuel:
Rho GTPases isoforms specificity in tumor cell migration and invasion. Conferencia Congreso no publicada. III Meeting in Cell Proliferation and Cancer. MALLORCA, ESPAÑA. 2008
Rho GTPases isoforms specificity in tumor cell migration and invasion. Conferencia Congreso no publicada. III Meeting in Cell Proliferation and Cancer. MALLORCA, ESPAÑA. 2008
Vega-Moreno, Francisco Manuel;Ridley, Anne J.:
Gene silencing technology for the study of Rho GTPases in tumor cell invasion and migration. Poster en Congreso. Gordon Research Conference: Mechanisms of Cell Signalling. . 2007
Gene silencing technology for the study of Rho GTPases in tumor cell invasion and migration. Poster en Congreso. Gordon Research Conference: Mechanisms of Cell Signalling. . 2007
Vega-Moreno, Francisco Manuel:
Gene silencing technology for the study of Rho GTPases in tumor cell invasion. Conferencia Congreso no publicada. Actin 2006 UK meeting. BRISTOL , REINO UNIDO. 2006
Gene silencing technology for the study of Rho GTPases in tumor cell invasion. Conferencia Congreso no publicada. Actin 2006 UK meeting. BRISTOL , REINO UNIDO. 2006
Vega-Moreno, Francisco Manuel;Ridley, Anne J.:
Gene silencing technology for the study of Rho GTPases in tumor cell invasion. Poster en Congreso. EMBO Worshop in Cell Migration, Tissue Invasion and Disease. CAPRI (ITALIA). 2006
Gene silencing technology for the study of Rho GTPases in tumor cell invasion. Poster en Congreso. EMBO Worshop in Cell Migration, Tissue Invasion and Disease. CAPRI (ITALIA). 2006
Vega-Moreno, Francisco Manuel:
The human kinase VRK1 and its role in the regulation of p53 tumor suppressor. Conferencia Congreso no publicada. XXVIII Congreso de la Sociedad española de Bioquimica y Biología Molecular (SEBBM). . 2005
The human kinase VRK1 and its role in the regulation of p53 tumor suppressor. Conferencia Congreso no publicada. XXVIII Congreso de la Sociedad española de Bioquimica y Biología Molecular (SEBBM). . 2005
Vega-Moreno, Francisco Manuel;Lazo, Pedro A.:
p53 phosphorylation by the human vaccinia-related kinase 1 (VRK1). Poster en Congreso. International p53 workshop. . 2002
p53 phosphorylation by the human vaccinia-related kinase 1 (VRK1). Poster en Congreso. International p53 workshop. . 2002
Artículos publicados
Colmenero-Repiso, Ana;Gómez, María De Los Ángeles;RODRIGUEZ-PRIETO, ISMAEL;Rivas-Infante, Eloy;Pardal-Redondo, Ricardo;Francisco M Vega:
Identification of VRK1 as a New Neuroblastoma Tumor Progression Marker Regulating Cell Proliferation. Cancers. 2020. Vol: 12. Núm: 11.
Identification of VRK1 as a New Neuroblastoma Tumor Progression Marker Regulating Cell Proliferation. Cancers. 2020. Vol: 12. Núm: 11.
Huertas, Carlos;Gómez, María De Los Ángeles;Pardal-Redondo, Ricardo;Francisco M Vega:
Hypoxia in the Initiation and Progression of Neuroblastoma Tumours. International Journal of Molecular Sciences. 2019. Vol: 21. Núm: 1. Pág. 39-53.
Hypoxia in the Initiation and Progression of Neuroblastoma Tumours. International Journal of Molecular Sciences. 2019. Vol: 21. Núm: 1. Pág. 39-53.
Linares-Clemente, Pedro;Mora, Jaume;Cabello-Laureano, Rosa María;Marquez-Vega, Catalina;Rivas-Infante, Eloy;Pardal-Redondo, Ricardo;Aguilar -Morante, Diana;RODRIGUEZ-PRIETO, ISMAEL;Ramirez-Villar, Gema Lucia;De Torres, Carolina;Santamaria, Vicente;Pascual-vaca, Diego;Colmenero-Repiso, Ana;Francisco M Vega:
Neural crest derived progenitor cells contribute to tumor stroma and aggressiveness in high-risk neuroblastoma . Oncotarget. 2017. Vol: 8. Núm: 52. Pág. 89775-89792. 10.18632/oncotarget.21128.
Neural crest derived progenitor cells contribute to tumor stroma and aggressiveness in high-risk neuroblastoma . Oncotarget. 2017. Vol: 8. Núm: 52. Pág. 89775-89792. 10.18632/oncotarget.21128.
Vega-Moreno, Francisco Manuel;Bolivar-Perez, Jorge;Pardal-Redondo, Ricardo;Garcia-Cozar, Francisco Jose;Aguado-Vidal, Enrique;Heck, Albert J.r. ;Duran-Ruiz, Mª Carmen;Gautier, Violette;Fernandez-Ponce, Cecilia;Extremera, Maria Jesus;Altelaar, A.f.m.;Millan, Jaime;Tellez, Juan C.;Hernandez-campos, Jose A;Conejero, Rosario:
The atheroma plaque secretome stimulates the mobilization of endothelial progenitor cells ex vivo. Journal of Molecular and Cellular Cardiology. 2017. Vol: 105. Pág. 12-23. 10.1016/j.yjmcc.2017.02.001.
The atheroma plaque secretome stimulates the mobilization of endothelial progenitor cells ex vivo. Journal of Molecular and Cellular Cardiology. 2017. Vol: 105. Pág. 12-23. 10.1016/j.yjmcc.2017.02.001.
Moura, David S.;Fernandez, Isabel F.;Marín-royo, Gema;López-sánchez, Inmaculada;Martín-doncel, Elena;Francisco M Vega;Lazo-zbikowsqui, Pedro A.:
Oncogenic Sox2 regulates and cooperates with VRK1 in cell cycle progression and differentiation. Scientific Reports. 2016. Vol: 6. 10.1038/srep28532.
Oncogenic Sox2 regulates and cooperates with VRK1 in cell cycle progression and differentiation. Scientific Reports. 2016. Vol: 6. 10.1038/srep28532.
Erdreich-epstein, Anat;Campan, Mihaela;Morales, Guillermo;Garlich, Joseph R.;Laird, Peter W. ;Seeger, Robert C. ;Shimada, Hiroyuki ;Durden, Donald L.;Singh, Alok R.;Joshi, Shweta ;Francisco M Vega;Guo, Pinzheng;Xu, Jingying;Groshen, Susan;Ye, Wei;Millard, Melissa:
Association of high microvessel ¿vß3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibi. Oncotarget. 2016. Vol: Nov 16. 10.18632/oncotarget.13386.
Association of high microvessel ¿vß3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibi. Oncotarget. 2016. Vol: Nov 16. 10.18632/oncotarget.13386.
Francisco M Vega;Ridley, Anne J.:
The RhoB small GTPase in physiology and disease. Small GTPases. 2016. Vol: Nov 2. Pág. 1-10. 10.1080/21541248.2016.1253528.
The RhoB small GTPase in physiology and disease. Small GTPases. 2016. Vol: Nov 2. Pág. 1-10. 10.1080/21541248.2016.1253528.
Francisco M Vega;Reymond, Nicolas;Thomas, Marian;Ridley, Anne J.:
The Rho GTPase RhoB regulates cadherin expression and epithelial cell-cell interaction . Cell Communication and Signaling [electronic resource]. 2015. Vol: 13. Núm: 6.
The Rho GTPase RhoB regulates cadherin expression and epithelial cell-cell interaction . Cell Communication and Signaling [electronic resource]. 2015. Vol: 13. Núm: 6.
Mártinez-criado, Yolanda;Cabella, Rosa;Fernández-pineda, Israel;Vega, F.M.:
Study of the expression of neural stem cell markers in neuroblastoma tumor samples and correlation with prognostic factors. Cirugía Pediátrica. 2013. Vol: 3. Pág. 112-118.
Study of the expression of neural stem cell markers in neuroblastoma tumor samples and correlation with prognostic factors. Cirugía Pediátrica. 2013. Vol: 3. Pág. 112-118.
Vega-Moreno, Francisco Manuel;Colomba, Audrey;Reymond, Nicolas;Thomas, Mairian;Ridley, Anne J.:
RhoB regulates cell migration through altered focal adhesion dynamics. Open Biology. 2012. Vol: 2. Núm: 5. 10.1186/s12964-015-0085-y.
RhoB regulates cell migration through altered focal adhesion dynamics. Open Biology. 2012. Vol: 2. Núm: 5. 10.1186/s12964-015-0085-y.
Reymond, Nicolas;Ridley, Anne J.;Vega-Moreno, Francisco Manuel:
Cdc42 promotes transendothelial migration of cancer cells through BETA1 integrin. Journal of Cell Biology. 2012. Vol: 199. Núm: 4. Pág. 653-668.
Cdc42 promotes transendothelial migration of cancer cells through BETA1 integrin. Journal of Cell Biology. 2012. Vol: 199. Núm: 4. Pág. 653-668.
Vega-Moreno, Francisco Manuel;Fruhwirth, G.;Ng, Tony;Ridley, Anne J.:
RhoA and RhoC have distinct roles in migration and invasion by acting through different targets. Journal of Cell Biology. 2011. Vol: 193. Núm: 4. Pág. 655-665.
RhoA and RhoC have distinct roles in migration and invasion by acting through different targets. Journal of Cell Biology. 2011. Vol: 193. Núm: 4. Pág. 655-665.
Valbuena, Alberto;Sanz-garcía, Marta;López-sánchez, I.;Vega-Moreno, Francisco Manuel;Lazo, Pedro A.:
Roles of VRK1 as a new player in the control of biological processes required for cell division. Cellular Signalling. 2010. Vol: 23. Núm: 8. Pág. 1267-1272.
Roles of VRK1 as a new player in the control of biological processes required for cell division. Cellular Signalling. 2010. Vol: 23. Núm: 8. Pág. 1267-1272.
Vega-Moreno, Francisco Manuel;Ridley, Anne J.:
Rho GTPases in cancer cell biology. FEBS Letters. 2008. Vol: 582. Núm: 14. Pág. 2093-2101.
Rho GTPases in cancer cell biology. FEBS Letters. 2008. Vol: 582. Núm: 14. Pág. 2093-2101.
Durán, María Del Carmen;Vega-Moreno, Francisco Manuel;Moreno-bueno, G.;Artiga, M.j.;Sánchez, L.;Palacios-Calvo, José;Ridley, Anne J.;Timms, J.f.:
Characterisation of tumoral markers correlated with ErbB2 (HER2/Neu) overexpression and metastasis in breast cancer. Proteomics. Clinical Applications. 2008. Vol: 2. Pág. 1313-1326.
Characterisation of tumoral markers correlated with ErbB2 (HER2/Neu) overexpression and metastasis in breast cancer. Proteomics. Clinical Applications. 2008. Vol: 2. Pág. 1313-1326.
Valbuena, Alberto;Blanco, Sandra;Vega-Moreno, Francisco Manuel;Lazo, Pedro A.:
The C/H3 domain of p300 is required to protect VRK1 and VRK2 from their downregulation induced by p53. PLoS One. 2008. Vol: 3. Núm: 7.
The C/H3 domain of p300 is required to protect VRK1 and VRK2 from their downregulation induced by p53. PLoS One. 2008. Vol: 3. Núm: 7.
Vega-Moreno, Francisco Manuel;Ridley, Anne J.:
Snapshot: Rho family GTPases. Cell. 2007. Vol: 129. Núm: 7. Pág. 1430-1431.
Snapshot: Rho family GTPases. Cell. 2007. Vol: 129. Núm: 7. Pág. 1430-1431.
Valbuena, Alberto;Lopez-sanchez, I.;Vega-Moreno, Francisco Manuel;Sevilla, Ana;Sanz-garcía, Marta;Blanco, Sandra;Lazo, Pedro A.:
Identification of a human epitope in human vaccinia-related kinase 1 (VRK1) and detection of different intracellular subpopulations. Archives of Biochemistry and Biophysics. 2007. Vol: 465. Núm: 1. Pág. 219-226.
Identification of a human epitope in human vaccinia-related kinase 1 (VRK1) and detection of different intracellular subpopulations. Archives of Biochemistry and Biophysics. 2007. Vol: 465. Núm: 1. Pág. 219-226.
Santos, Claudio R.;De Alava, Enrique;Sanchez-cespedes, M.;Lazo, Pedro A.;Rodriguez-pinilla, M.;Vega-Moreno, Francisco Manuel;Rodriguez-peralto, J.l.;Blanco, Sandra;Sevilla, Ana;Valbuena, Alberto;Hernandez, T.;Van Wijnen, A.j.:
VRK1 Signaling pathway in the context of the proliferation phenotype in Head and Neck squamous cell carcinoma. Molecular Cancer Research. 2006. Vol: 4. Núm: 3. Pág. 177-185.
VRK1 Signaling pathway in the context of the proliferation phenotype in Head and Neck squamous cell carcinoma. Molecular Cancer Research. 2006. Vol: 4. Núm: 3. Pág. 177-185.
Blanco, Sandra;Klimcakova, L.;Vega-Moreno, Francisco Manuel;Lazo, Pedro A.:
Subcellular localization of vaccinia-related kinase 2 (VRK2) isoforms determines their different effects on p53 stability in tumour cell lines. The FEBS Journal. 2006. Vol: 273. Núm: 1. Pág. 2487-2504.
Subcellular localization of vaccinia-related kinase 2 (VRK2) isoforms determines their different effects on p53 stability in tumour cell lines. The FEBS Journal. 2006. Vol: 273. Núm: 1. Pág. 2487-2504.
Wheeler, A.p.;Wells, C.;Smith, S.d.;Vega-Moreno, Francisco Manuel;Herderson, R.b.;Tybulewicz, V.l.;Ridley, Anne J.:
Rac1 and Rac2 regulate macrophage morphology but are not essential for migration. Journal of Cell Science. 2006. Vol: 19. Núm: 13. Pág. 2749-2757.
Rac1 and Rac2 regulate macrophage morphology but are not essential for migration. Journal of Cell Science. 2006. Vol: 19. Núm: 13. Pág. 2749-2757.
Valbuena, Alberto;Vega-Moreno, Francisco Manuel;Lazo, Pedro A.:
p53 downregulates its activating vaccinia-related kinase 1 (VRK1) forming a new autoregulatory loop. Molecular and Cellular Biology. 2006. Vol: 26. Núm: 13. Pág. 4782-4793.
p53 downregulates its activating vaccinia-related kinase 1 (VRK1) forming a new autoregulatory loop. Molecular and Cellular Biology. 2006. Vol: 26. Núm: 13. Pág. 4782-4793.
Sevilla, Ana;Santos, Claudio R.;Barcia, Ramón;Vega-Moreno, Francisco Manuel;Lazo, Pedro A.:
c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK). Oncogene. 2004. Vol: 23. Núm: 55. Pág. 8950-8958.
c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK). Oncogene. 2004. Vol: 23. Núm: 55. Pág. 8950-8958.
Sevilla, Ana;Santos, Claudio R.;Vega-Moreno, Francisco Manuel;Lazo, Pedro A.:
Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with J. Journal of Biological Chemistry. 2004. Vol: 279. Núm: 26. Pág. 27458-27465.
Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with J. Journal of Biological Chemistry. 2004. Vol: 279. Núm: 26. Pág. 27458-27465.
Vega-Moreno, Francisco Manuel;Sevilla, Ana;Lazo, Pedro A.:
p53 Stabilization and accumulation induced by human vaccinia-related kinase 1. Molecular and Cellular Biology. 2004. Vol: 24. Núm: 23. Pág. 10366-10380.
p53 Stabilization and accumulation induced by human vaccinia-related kinase 1. Molecular and Cellular Biology. 2004. Vol: 24. Núm: 23. Pág. 10366-10380.
Santos, Claudio R.;Vega-Moreno, Francisco Manuel;Blanco, Sandra;Barcia, Ramón;Lazo, Pedro A.:
The vaccinia virus B1R kinase induces p53 downregulation by and Mdm2-dependent mechanism. Virology. 2004. Vol: 328. Núm: 2. Pág. 254-265.
The vaccinia virus B1R kinase induces p53 downregulation by and Mdm2-dependent mechanism. Virology. 2004. Vol: 328. Núm: 2. Pág. 254-265.
Vega-Moreno, Francisco Manuel;Gonzalo, P.;Gaspar, Maria Luisa;Lazo, Pedro A.:
Expression of the VRK (vaccinia-related kinase) gene family of p53 regulators in murine hematopoietic development. FEBS Letters. 2003. Vol: 544. Pág. 176-180.
Expression of the VRK (vaccinia-related kinase) gene family of p53 regulators in murine hematopoietic development. FEBS Letters. 2003. Vol: 544. Pág. 176-180.
Barcia, Ramón;Lopez-borges, Susana;Vega-Moreno, Francisco Manuel;Lazo, Pedro A.:
Kinetic properties of p53 phosphorylation by the human vaccinia-related kinase 1. Archives of Biochemistry and Biophysics. 2002. Vol: 399. Pág. 1-5.
Kinetic properties of p53 phosphorylation by the human vaccinia-related kinase 1. Archives of Biochemistry and Biophysics. 2002. Vol: 399. Pág. 1-5.
Martín-Rubio, María Esther;Hidalgo-Jimenez, Josefina;Vega-Moreno, Francisco Manuel;Velasco-Lopez, Angel:
Trimeric G proteins modulate the dynamic interaction of PKAII with the Golgi complex. Journal of Cell Science. 1999. Vol: 112. Núm: 22. Pág. 3869-3878.
Trimeric G proteins modulate the dynamic interaction of PKAII with the Golgi complex. Journal of Cell Science. 1999. Vol: 112. Núm: 22. Pág. 3869-3878.
Tesis dirigidas o codirigidas
Colmenero-Repiso, Ana:
Papel de la quinasa humana VRK1 en la biología del neuroblastoma. Tesis Doctoral. 2020
Papel de la quinasa humana VRK1 en la biología del neuroblastoma. Tesis Doctoral. 2020
